AGITATION
Clinical trials for AGITATION explained in plain language.
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New hope for Alzheimer's agitation: Long-Term safety trial underway
Symptom relief Recruiting nowThis study is testing the long-term safety of a combination of two drugs, KarXT and KarX-EC, for treating agitation in people with Alzheimer's disease. It is an open-label extension, meaning everyone knows they are getting the treatment. The study enrolls 600 participants who hav…
Matched conditions: AGITATION
Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Symptom relief
Last updated Jul 02, 2026 04:00 UTC
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New patch could ease agitation for Alzheimer's patients
Symptom relief Recruiting nowThis study tests a medicated skin patch (dexmedetomidine) to see if it can reduce agitation in people with Alzheimer's dementia. About 150 adults living in care facilities will receive either the patch or a placebo for 96 hours. The goal is to measure changes in agitated behavior…
Matched conditions: AGITATION
Phase: PHASE2 • Sponsor: Teikoku Pharma USA, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New pill could calm agitation in Alzheimer's patients
Symptom relief Recruiting nowThis study tests an experimental oral medication (BMS-986368) to reduce agitation in people with Alzheimer's disease. About 120 participants will receive either a low dose, high dose, or placebo. The main goal is to see if the drug safely decreases agitated behaviors, such as pac…
Matched conditions: AGITATION
Phase: PHASE2 • Sponsor: Celgene • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Robotic seal aims to soothe Post-Surgery agitation
Symptom relief Recruiting nowThis study tests whether a robotic seal named PARO can reduce agitation, anxiety, and pain in patients recovering from visceral surgery. 300 adults having elective surgery will either use PARO or not, and their agitation levels will be tracked for three days. The goal is to find …
Matched conditions: AGITATION
Phase: NA • Sponsor: Hannover Medical School • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can a Cannabis-Like drug soothe Alzheimer's agitation?
Symptom relief Recruiting nowThis study tests whether nabilone, a synthetic cannabinoid, can safely reduce agitation in people with Alzheimer's disease. Agitation is common and distressing, with few good treatment options. About 112 participants will receive either nabilone or a placebo for 8 weeks, and rese…
Matched conditions: AGITATION
Phase: PHASE3 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Hope for Alzheimer's agitation: new drug enters final testing
Symptom relief Recruiting nowThis study tests whether masupirdine, a daily tablet, can safely reduce agitation in people with Alzheimer's dementia. About 375 participants will receive either masupirdine or a placebo. The main goal is to see if the drug improves agitation symptoms, which can include aggressio…
Matched conditions: AGITATION
Phase: PHASE3 • Sponsor: Suven Life Sciences Limited • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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New brain monitor could help ICU patients stay calm and aware
Knowledge-focused Recruiting nowThis study is testing a new, non-invasive brain monitor (Neurosteer) in 100 ICU patients who are on breathing machines and sedatives. The monitor is a small device placed on the forehead that measures brain activity. Researchers want to see if it can accurately track levels of se…
Matched conditions: AGITATION
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC