ADVANCED SOFT TISSUE SARCOMA
Clinical trials for ADVANCED SOFT TISSUE SARCOMA explained in plain language.
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Experimental combo targets Hard-to-Treat sarcomas
Disease control OngoingThis study tests a combination of two drugs—HDM201 and pazopanib—in people with advanced or metastatic soft tissue sarcoma that has a normal p53 gene. The trial has two parts: first, finding the safest dose of HDM201 when given with a fixed dose of pazopanib, and second, checking…
Matched conditions: ADVANCED SOFT TISSUE SARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Centre Leon Berard • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New drug cocktail shows promise in slowing rare sarcoma
Disease control OngoingThis study tests whether adding two immunotherapy drugs (zalifrelimab and balstilimab) to standard chemotherapy (doxorubicin) can help control advanced or metastatic soft tissue sarcoma for longer. About 65 adults with sarcoma that cannot be removed by surgery will receive the co…
Matched conditions: ADVANCED SOFT TISSUE SARCOMA
Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Promising combo tackles rare sarcoma in early trial
Disease control OngoingThis study tests a combination of two drugs, lurbinectedin and doxorubicin, in people with advanced soft-tissue sarcoma or leiomyosarcoma that cannot be cured with standard treatments. The first part finds a safe dose, and the second part compares the combination to lurbinectedin…
Matched conditions: ADVANCED SOFT TISSUE SARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC