ADVANCED SOFT TISSUE SARCOMA
Clinical trials for ADVANCED SOFT TISSUE SARCOMA explained in plain language.
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Promising drug combo targets rare sarcoma in early trial
Disease control OngoingThis study tests a new combination of two drugs, lurbinectedin and doxorubicin, for people with advanced leiomyosarcoma, a rare soft tissue cancer. The first part finds a safe dose, and the second part compares the combination to lurbinectedin alone to see which works better. Abo…
Matched conditions: ADVANCED SOFT TISSUE SARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New drug combo shows promise for rare sarcoma
Disease control OngoingThis study tests a combination of two drugs, HDM201 and pazopanib, in people with advanced soft tissue sarcoma that has spread. The goal is to find the safest dose and see if the combination can help control the cancer. About 47 adults whose tumors have a specific genetic feature…
Matched conditions: ADVANCED SOFT TISSUE SARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Centre Leon Berard • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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New combo therapy aims to stall sarcoma progression
Disease control OngoingThis study tests whether adding two immunotherapy drugs (zalifrelimab or botensilimab plus balstilimab) to standard chemotherapy (doxorubicin) can keep advanced soft tissue sarcoma from growing longer than chemo alone. About 65 adults with sarcoma that has spread or cannot be rem…
Matched conditions: ADVANCED SOFT TISSUE SARCOMA
Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Apr 29, 2026 15:03 UTC