ADVANCED OVARIAN CARCINOMA

This study tests if a less invasive surgery (laparoscopy) works as well as or better than standard open surgery for people with advanced ovarian, fallopian tube, or peritoneal cancer who have already had chemotherapy. About 580 participants will be randomly assigned to one of the…

This early-phase study tests an experimental pill, NKT3964, designed to break down a protein (CDK2) that helps cancer cells grow. About 150 adults with advanced or metastatic solid tumors (including ovarian, endometrial, breast, gastric, and lung cancers) that have stopped respon…

This early-phase study tests a wearable device that creates low-intensity electric fields (tumor treating fields) combined with either cabozantinib or a chemo-immunotherapy pair (nab-paclitaxel and atezolizumab) in people with advanced solid tumors in the abdomen or chest. The go…

This study tests a vaccine made from a patient's own white blood cells, designed to train the immune system to attack ovarian cancer cells. It is for people with advanced stage III or IV ovarian, fallopian tube, or primary peritoneal cancer. The goal is to see if the vaccine can …

This study tests whether taking probiotics (friendly bacteria) can improve gut and vaginal health in 161 women with advanced or recurrent ovarian cancer who are receiving platinum chemotherapy. Researchers will check changes in the microbiome, quality of life, and symptoms. The g…

This study tests a supportive telehealth program called REVITALIZE to see if it can reduce how much fatigue interferes with daily life for adults with advanced ovarian cancer who are taking PARP inhibitor maintenance therapy. About 240 participants will either receive the REVITAL…

This study compares giving cancer treatment at home versus in a clinic for people with advanced cancers. The goal is to see if home treatment reduces stress, financial burden, and improves the overall experience. About 220 participants will be randomly assigned to receive their t…