ADVANCED OR METASTATIC SOLID TUMORS
Clinical trials for ADVANCED OR METASTATIC SOLID TUMORS explained in plain language.
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New pill targets advanced cancers in first human tests
Disease control OngoingThis early-stage study is testing a new oral drug called ERAS-601 in adults with advanced solid tumors that have spread. The main goals are to find the safest and most effective dose, both when given alone and when combined with other cancer therapies. Researchers will also check…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: Erasca, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New Two-Drug attack targets Tough-to-Treat cancer mutation
Disease control OngoingThis study is testing the safety and early effectiveness of a new drug combination (naporafenib plus trametinib) for people with advanced solid tumors that have a specific genetic change called a RAS Q61X mutation. It is for patients aged 12 and older whose cancer has grown despi…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: Erasca, Inc. • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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New cancer drug seeks right dose to fight tough tumors
Disease control OngoingThis early-stage trial is testing a new drug called WTX-330 in adults with advanced solid tumors or non-Hodgkin lymphoma that have stopped responding to standard treatments. The main goals are to find the safest and most effective dose and to see if the drug can shrink tumors. Re…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Werewolf Therapeutics, Inc. • Aim: Disease control
Last updated Mar 06, 2026 15:38 UTC
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Cancer drug gets a shot in the arm: testing a new, easier injection method
Knowledge-focused OngoingThis early-stage study is testing a new way to give the cancer drug pembrolizumab—as an injection under the skin instead of into a vein. The main goal is to see how much of the drug gets into the bloodstream and to check its safety when given this way. It involves 72 people with …
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC