ADVANCED OR METASTATIC SOLID TUMORS
Clinical trials for ADVANCED OR METASTATIC SOLID TUMORS explained in plain language.
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Experimental pill takes on advanced cancers alongside immunotherapy
Disease control CompletedThis early-phase trial tests an experimental oral drug, MK-6598, both by itself and in combination with the immunotherapy pembrolizumab (Keytruda) in adults with advanced or metastatic solid tumors. The main goals are to check safety, find the right dose, and see early signs of t…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New shot form of cancer drug tested in 142 patients
Disease control CompletedThis study tested a new under-the-skin shot version of the cancer drug pembrolizumab (Keytruda) in 142 people with advanced solid tumors. The goal was to see how well the body absorbs the drug compared to the standard IV infusion. Researchers also checked for side effects and how…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New drug shows promise for Hard-to-Treat cancers
Disease control CompletedThis study tested a new drug called MRG004A in 39 adults with advanced or metastatic solid tumors that have a specific marker called tissue factor. The goal was to find the safest dose and see if the drug can shrink tumors. Researchers monitored side effects and how well the drug…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Lepu Biopharma Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Experimental drug BAT8010 tested in patients with advanced cancers
Disease control CompletedThis early-phase trial tested an experimental drug called BAT8010 in 23 people with advanced or metastatic solid tumors who had no other standard treatment options. The main goals were to check safety, find the best dose, and see if the drug shows any sign of shrinking tumors. Pa…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: Bio-Thera Solutions • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New drug cocktail targets tough cancers in early trial
Disease control CompletedThis early-phase study tested a combination of two drugs, temsirolimus and cetuximab, in 45 adults with advanced or metastatic solid tumors that had not responded to standard treatments. The goal was to check safety and see if blocking two cancer pathways at once could slow tumor…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New cancer drug WTX-330 shows promise in early human trial
Disease control CompletedThis early-phase study tested a new drug called WTX-330 in 25 adults with advanced solid tumors or lymphoma that had stopped responding to standard treatments. The main goals were to check safety, find the right dose, and see if the drug could shrink tumors. The study is now comp…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: Werewolf Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New combo therapy shows promise for Hard-to-Treat cancers
Disease control CompletedThis study tested a new drug, TAK-981, combined with the immunotherapy pembrolizumab in 161 adults with advanced or metastatic solid tumors that could not be cured. The main goals were to check safety and see if the combination could shrink tumors. Participants received treatment…
Matched conditions: ADVANCED OR METASTATIC SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC