ADULT SOLID NEOPLASM
Clinical trials for ADULT SOLID NEOPLASM explained in plain language.
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New Vaccine-Immunotherapy combo shows promise for Hard-to-Treat cancers
Disease control OngoingThis early-phase study tested a vaccine (p53MVA) plus the drug pembrolizumab in 11 adults with advanced solid tumors that had stopped responding to other treatments. The goal was to see if the combination is safe and can boost the immune system to attack cancer cells. Participant…
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 17, 2026 02:04 UTC
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New drug combo tested for Hard-to-Treat cancers
Disease control OngoingThis early-stage trial studies how two different doses of vorinostat work with standard chemotherapy drugs (carboplatin or paclitaxel) in 20 adults with advanced solid tumors that have not responded to other treatments. The goal is to find safe dose levels and measure how the dru…
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New drug combo shows promise for Hard-to-Treat cancers
Disease control OngoingThis early-phase study tested the safety and best dose of two drugs, ixabepilone and temsirolimus, given together to adults with advanced solid tumors that had spread or couldn't be surgically removed. The goal was to find the highest safe dose and see how well the combination wo…
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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Experimental drug cocktail targets Hard-to-Treat cancers
Disease control OngoingThis early-phase trial tests a combination of two targeted drugs (vismodegib and erlotinib) with or without a standard chemotherapy drug (gemcitabine) in people with advanced pancreatic cancer or other solid tumors that cannot be surgically removed. The main goal is to find the s…
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 08, 2026 12:04 UTC
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New drug combo shows promise for Hard-to-Treat cancers
Disease control OngoingThis early-phase trial tests the safety and best dose of combining two drugs, erlotinib and irinotecan, in 60 adults with advanced solid tumors that have not responded to standard treatments. The goal is to see if the combination can shrink tumors or slow their growth. Participan…
Matched conditions: ADULT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 07, 2026 18:41 UTC