ACUTE RENAL FAILURE
Clinical trials for ACUTE RENAL FAILURE explained in plain language.
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New dialyzer shows promise in small safety trial
Disease control CompletedThis study tested a new dialysis filter called ELISIO-HX in 22 adults with kidney failure. Participants used the new filter three times a week for 12 weeks. The goal was to see if it safely maintained albumin levels while improving removal of certain waste products. The trial is …
Matched conditions: ACUTE RENAL FAILURE
Phase: NA • Sponsor: Nipro Medical Corporation • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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When to transfuse? study tests best blood strategy for heart patients after surgery
Disease control CompletedThis study looked at 1,424 veterans at high risk for heart problems who had major surgery. It compared two approaches to blood transfusion: a liberal strategy (transfusing when hemoglobin drops below 10) versus a restrictive strategy (transfusing only when hemoglobin drops below …
Matched conditions: ACUTE RENAL FAILURE
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Alcohol lock may stop deadly infections in ICU patients
Prevention CompletedThis study tested a 60% ethanol (alcohol) lock solution to prevent serious catheter infections in 1,460 ICU patients with acute kidney failure needing dialysis. The ethanol lock is placed inside the catheter to kill germs. The goal was to see if it reduces major catheter-related …
Matched conditions: ACUTE RENAL FAILURE
Phase: PHASE3 • Sponsor: University Hospital, Clermont-Ferrand • Aim: Prevention
Last updated Jun 27, 2026 12:35 UTC
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Massive VA trial tests cheap ways to protect kidneys during heart procedures
Prevention CompletedThis large study tested whether giving sodium bicarbonate (a type of fluid) or N-acetylcysteine (a supplement) before and after angiography could prevent serious kidney problems, including death or need for dialysis. Over 5,000 high-risk patients with kidney disease took part. Th…
Matched conditions: ACUTE RENAL FAILURE
Phase: PHASE3 • Sponsor: VA Office of Research and Development • Aim: Prevention
Last updated Jun 27, 2026 07:56 UTC
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Contrast dye test reveals hidden kidney damage in ICU survivors
Knowledge-focused CompletedThis study uses a dye called iohexol to measure how well the kidneys are working in patients leaving the intensive care unit after acute kidney failure. The goal is to find out how many patients still have reduced kidney function even though their standard blood tests look normal…
Matched conditions: ACUTE RENAL FAILURE
Phase: PHASE3 • Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Simple urine test may predict kidney recovery after acute failure
Knowledge-focused CompletedThis study looked at 287 patients with acute kidney injury caused by tubular necrosis. Researchers measured two substances in urine (PIIINP and NGAL) to see if they could predict whether kidney function would return or if chronic kidney disease would develop. The goal is to find …
Matched conditions: ACUTE RENAL FAILURE
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Scientists collect kidney samples from COVID-19 patients to uncover clues about organ damage
Knowledge-focused CompletedThis completed study collected blood, urine, and kidney tissue from 90 COVID-19 patients with acute kidney injury. Researchers aimed to build a biorepository and analyze samples to better understand how COVID-19 affects the kidneys. The goal is to speed up discoveries and improve…
Matched conditions: ACUTE RENAL FAILURE
Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Smart alerts cut kidney risks for seniors in hospital
Knowledge-focused CompletedThis study tested a computer system that alerts pharmacists about potential kidney failure or high potassium risks in older hospital patients. Researchers wanted to see if these alerts, combined with pharmacist reviews, could reduce serious side effects from medications. The stud…
Matched conditions: ACUTE RENAL FAILURE
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC