ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Clinical trials for ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME explained in plain language.
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New transplant strategy aims to tame tough blood cancers
Disease control OngoingThis study is testing a two-drug chemotherapy regimen followed by a donor stem cell transplant for adults with certain blood cancers that are in remission or at high risk. The goal is to see if this approach can better control the disease and prevent it from coming back after the…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New drug duo aims to control aggressive blood cancers
Disease control OngoingThis study is testing the safety and effectiveness of combining two drugs, vorinostat and azacitidine, for patients with myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML). The goal is to find the best dose and see if the combination can better control the disease by…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Immune-Boosting drug joins fight against tough blood cancer in seniors
Disease control OngoingThis study is testing if adding an immunotherapy drug (pembrolizumab) to a standard two-drug combination works better for older adults with newly diagnosed acute myeloid leukemia (AML) who cannot have intensive chemotherapy. The goal is to see if the three-drug combo helps more p…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New antibody drug enters human testing for Tough-to-Treat blood cancers
Disease control OngoingThis is a first-in-human study to find a safe dose of an experimental antibody drug called Hu8F4 for patients with advanced blood cancers like leukemia and myelodysplastic syndrome (MDS). The main goals are to check for side effects and see how the body processes the drug. The st…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New hope for Tough-to-Treat leukemia: experimental drug added to standard chemo
Disease control OngoingThis study is testing a new drug called pevonedistat, given alongside standard chemotherapy drugs, for adults newly diagnosed with high-risk acute myeloid leukemia (AML). The main goals are to find the safest and most effective dose of the new combination and to see if it helps m…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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New hope for tough blood cancers: testing a powerful drug duo
Disease control OngoingThis study is testing a combination of two drugs for people with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) that has come back or hasn't responded to other treatments. The goal is to see if the combination is safe and effective at controlling the dis…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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New pill trial targets genetic flaw in tough blood cancers
Disease control OngoingThis study is testing if a pill called olaparib can help control advanced blood cancers (acute myeloid leukemia or myelodysplastic syndrome) that have come back or haven't responded to standard treatments. It is for adults whose cancer has a specific genetic change called an IDH …
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New hope for AML patients: can a Cancer-Fighting drug boost Chemo's power?
Disease control OngoingThis study is testing if adding the immunotherapy drug pembrolizumab to standard chemotherapy works better for adults newly diagnosed with acute myeloid leukemia (AML). The goal is to see if the combination helps more patients achieve a deep remission with no detectable cancer ce…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Scientists test 'Double Hit' combo against tough blood cancers
Disease control OngoingThis study is testing if adding a new drug called veliparib to a standard two-drug chemotherapy works better for people with advanced blood cancers that have spread and are hard to treat. It will compare the two-drug combo with the three-drug combo in about 25 participants to see…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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New hope for tough leukemia in younger patients
Disease control OngoingThis study is testing how well a chemotherapy drug called CPX-351 works for adults under 60 with secondary acute myeloid leukemia, a type of blood cancer that develops from other blood disorders or previous cancer treatments. The goal is to see if this drug can help patients achi…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Scientists test new pill to boost power of leukemia chemotherapy
Disease control OngoingThis early-stage study is testing a new oral drug called navtemadlin (KRT-232) in combination with standard chemotherapy for adults newly diagnosed with a fast-growing blood cancer called acute myeloid leukemia (AML). The main goals are to find the safest and most effective dose …
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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Phone therapy trial aims to ease debilitating cancer fatigue
Symptom relief OngoingThis study is testing whether a type of talk therapy, delivered over the phone, can help patients with acute myeloid leukemia (AML) or lymphoma manage severe, long-lasting cancer-related fatigue. The therapy focuses on teaching patients skills to change unhelpful thoughts and beh…
Matched conditions: ACUTE MYELOID LEUKEMIA ARISING FROM PREVIOUS MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Mar 12, 2026 13:50 UTC