ACUTE HEART FAILURE

This study tested whether a lower oxygen target (90% saturation) or a higher one (96% saturation) is better for people hospitalized with acute heart failure and fluid buildup in the lungs. 122 adults were randomly assigned to one of two groups using a special oxygen-delivery robo…

This study tested whether a structured plan for giving diuretics (water pills) to patients hospitalized with worsening chronic heart failure is safer and more effective than usual care. About 299 adults took part. The goal was to see if the protocol helped patients lose excess fl…

This study looked at whether a 7-day course of prednisone, a steroid, can lower inflammation in people with acute heart failure. 101 adults from the emergency department took part. The main goal was to see if prednisone plus usual care reduced C-reactive protein (a marker of infl…

This study looked at whether adding empagliflozin (a diabetes drug) to standard water pills helps people with acute heart failure and moderate-to-severe kidney disease urinate out more excess fluid. 25 adults participated, and researchers measured urine output after combining the…

This study tested a device called preCARDIA that temporarily blocks a large vein in the chest to help people with severe heart failure who are not getting better with standard treatments. The study included 60 adults with advanced heart failure. The goal was to see if the device …

This study tested whether a 7-day course of the steroid prednisone, started in the emergency department, could lower inflammation in patients with acute heart failure. Only 3 people took part, and the main goal was to see changes in a blood marker called C-reactive protein (CRP).…

This study looked at 64 people hospitalized for acute heart failure to see if a blood marker called cystatin C could predict kidney problems caused by diuretic (water pill) treatment. Researchers measured cystatin C levels daily and compared them to standard kidney tests. The goa…