ACUTE CORONARY SYNDROMES

This study looks for the best type and dose of a single blood thinner (P2Y12 inhibitor) for people who have had a heart stent placed. About 355 participants will try different doses to find the sweet spot that prevents blood clots without raising bleeding risk. The goal is to per…

This early-stage trial tests whether a new drug called UDP-003 is safe in healthy adults and people with heart disease. About 84 participants will receive either the drug or a placebo. The study also looks at how the drug moves through the body and if it might help treat heart co…

This study looks at whether adding oregano and basil leaves to the diet can lower inflammation and improve cholesterol in people who have recently had unstable angina. About 70 participants will eat these herbs and have their blood and urine tested. The goal is to see if these co…

This study tests a new type of heart stent made from magnesium that dissolves over time. It is designed for people with long blockages in their coronary arteries. The goal is to see if it is safe and effective at keeping arteries open and reducing heart-related problems. About 10…

This study tests a drug called orticumab in 240 people who had a heart attack and still have high inflammation in their heart arteries. The goal is to see if orticumab can lower that inflammation better than a placebo over 6 months. Participants will have CT scans to measure infl…

This study tests a new rapid blood test done at the patient's bedside to quickly rule out a type of heart attack (NSTEMI) in people with chest pain. About 1,550 adults visiting the emergency room will be randomly assigned to either the new rapid test or the standard lab test. The…

This study tests whether using a hand fan can prevent or reduce shortness of breath caused by the heart drug ticagrelor. About 110 adults with acute coronary syndrome who are starting ticagrelor will be enrolled. Researchers will track how many people have breathing trouble withi…

This study looks at immune cells called macrophages in the arteries of people with heart disease or poor leg circulation. Researchers will use imaging and blood tests to see how these cells are activated. The goal is to better understand the disease, not to test a new treatment. …

This study looks at 100 people hospitalized for a heart attack. Researchers will test a new device called Cor-IS that measures how well blood vessels widen. The goal is to see if this measurement can help predict future heart problems like another heart attack or stroke.