ACNE VULGARIS

This study tested the acne cream Winlevi in 10 people with darker skin tones (Fitzpatrick types IV, V, VI). The goal was to see how well it cleared or nearly cleared acne after 16 weeks. Acne is very common, but there is little research focused on skin of color, so this study hel…

This study tested whether a facial moisturizer is gentle and helpful for people with mild to moderate acne. 47 participants used the product for 4 weeks. Researchers checked skin dryness, redness, pores, and overall appearance, and asked participants how their skin felt. The goal…

This study tested whether oral metformin, a common diabetes medication, can treat moderate to severe acne. Researchers compared it to doxycycline, a standard antibiotic for acne, in 68 people aged 12 to 40. Participants took either metformin twice daily or doxycycline once daily …

This study tested a new gel called IDP-126 against a standard acne treatment (Epiduo® Forte) and a placebo gel. About 686 people with moderate to severe acne used the gel once daily for 12 weeks. Researchers measured how much acne lesions decreased and how clear the skin became.

This study tested whether adding a non-invasive ear acupressure technique to a standard acne cream (adapalene) works better than the cream alone. Sixty-four people with mild to moderate acne took part. The goal was to see if the combination reduced acne severity and lesion counts…

This study tested a combination of two topical medications—Winlevi and adapalene 0.3% gel—for treating acne vulgaris. Twenty participants aged 12 and older used the combo for 16 weeks. The main goal was to see how many achieved clear or nearly clear skin, with additional measures…

This study tested whether adding vitamin D supplements to standard acne medication (azithromycin and a topical retinoid) improves acne more than medication alone. Fifty-eight people with acne vulgaris took part for two months. Researchers measured changes in acne severity using a…

This study tested a new drug called imsidolimab in 123 people with moderate-to-severe acne. The goal was to see if it reduces the number of pimples and inflamed spots on the face compared to a placebo. The trial lasted 12 weeks and measured changes in lesion counts.

This study tested a treatment called dextrose phonophoresis for mild to moderate acne. It involved 115 people aged 18 to 30. The treatment uses ultrasound to help a sugar solution (dextrose) penetrate the skin, aiming to reduce acne lesions and severity. The study is now complete…

This study tested a gel containing dapsone (7.5%) against a placebo gel in 100 adults with mild-to-moderate acne. Participants applied the gel once daily for 8 weeks, and researchers tracked changes in acne lesions, skin oil, redness, and quality of life. The goal was to see if t…

This study looked at whether taking probiotics can reduce a protein in the blood linked to acne inflammation. Researchers measured this protein in 50 adults with mild to moderate acne before and after probiotic treatment. The goal was to see if probiotics could help ease acne sym…

This early-stage study tested a new topical medicine (PF-07905428) for acne. It involved 52 healthy volunteers and people with moderate to severe acne, aged 18 to 40. The cream was applied daily for 2 to 4 weeks. The main goal was to check safety and how the body processes the dr…

This study tested whether a generic tretinoin gel works as well as the brand-name Retin-A Micro for treating acne. Over 1,000 people with mild to moderate acne used one of the gels or a placebo for several weeks. The goal was to see if the generic version reduces pimples and blac…