ACL
Clinical trials for ACL explained in plain language.
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New ACL graft shows promise in tiny trial
Disease control CompletedThis study tested a new material called OrthoPure XT for repairing torn anterior cruciate ligaments (ACL) in the knee. Ten patients received the graft and were followed with questionnaires and MRI scans to assess knee function, pain, and healing. The goal was to see if OrthoPure …
Matched conditions: ACL
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated Jun 26, 2026 16:42 UTC
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New nerve block combo may cut opioid use after ACL repair
Symptom relief CompletedThis study tested whether adding genicular nerve blocks to standard pain blocks could reduce opioid use and pain after ACL knee surgery. 192 adults having outpatient ACL repair were randomly assigned to get the extra blocks or standard care. The goal was to see if the new approac…
Matched conditions: ACL
Phase: PHASE4 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Scientists uncover muscle secrets behind ACL injuries in athletes
Knowledge-focused CompletedThis study looked at how trunk and leg muscles work together to load the ACL during a single-leg landing in 40 male college athletes. Researchers used motion capture and muscle models to estimate ACL force. The goal was to find muscle patterns that could help prevent ACL injuries…
Matched conditions: ACL
Sponsor: Universiti Sains Malaysia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Which ACL graft gets footballers back on the field faster?
Knowledge-focused CompletedThis study looked at 54 young male football players who had ACL surgery using either a quadriceps tendon graft or a semitendinosus tendon graft. The goal was to see which method leads to better leg strength and a higher rate of returning to sports within two years. The results he…
Matched conditions: ACL
Phase: NA • Sponsor: Universidad de Granada • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Treadmill trick may boost ACL recovery
Knowledge-focused CompletedThis study tested whether walking on a treadmill with belts moving at different speeds can improve how the knee loads weight after ACL reconstruction. Thirty-two participants who had ACL surgery within the past 10 months walked on the treadmill for 20 minutes. Researchers measure…
Matched conditions: ACL
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC