Varicose disease
MONDO:0008638A vascular disease characterized by the presence of enlarged and tortuous veins.
Also known as: varix, varices, varicose veins
180 clinical trials for this condition and its sub-types, 40 tagged with Varicose disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Varicose disease
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Pelvic varices 1 trial · 86 incl. sub-types
3 sub-types
- Hemorrhoid 69 trials · 72 incl. sub-types Sub-types →
- Varicocele 15 trials
- Vulval varices 0 trials
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Esophageal varices 34 trials · 55 incl. sub-types
2 sub-types
- Esophageal varices with bleeding 29 trials
- Esophageal varices without bleeding 0 trials
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Mesenteric varices 0 trials
Most studied deeper sub-types
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New laser shows promise for varicose vein treatment in Head-to-Head trial
Disease control OngoingThis phase 3 trial compares two laser wavelengths (1940 nm vs 1470 nm) for closing off faulty veins in people with symptomatic varicose veins. 220 adults will be randomly assigned to one laser or the other. The main goal is to see which laser achieves complete vein closure at 6 m…
Phase 3 • Sponsor: Kafrelsheikh University • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Longer compression may prevent dark spots after varicose vein treatment
Symptom relief OngoingThis study looks at whether wearing compression stockings for a longer time after foam sclerotherapy (a treatment for varicose veins) can reduce skin darkening (hyperpigmentation) above the treated veins. About 140 adults with varicose veins will be followed for 28 days after the…
Sponsor: Pirogov Russian National Research Medical University • Aim: Symptom relief
Last updated Sep 18, 2026 00:00 UTC
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Tighter stockings after vein surgery: do they really help more?
Symptom relief OngoingThis trial tests whether wearing compression stockings with a higher (32 mmHg) or lower (21 mmHg) pressure after radiofrequency ablation for varicose veins leads to less pain and swelling. About 64 adults with varicose veins and leg swelling will wear one of the two stocking type…
Sponsor: IRCCS Policlinico S. Donato • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Hidden pelvic vein issues may sabotage leg vein surgery, study warns
Knowledge-focused OngoingThis study looks at how often pelvic congestion syndrome (a condition where veins in the pelvis become enlarged and painful) occurs in women who are about to have a standard procedure for leg varicose veins. Researchers want to know if having this pelvic condition affects how muc…
Sponsor: Chengdu University of Traditional Chinese Medicine • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Scientists track varicose veins from start to worse
Knowledge-focused OngoingThis study follows 100 people with and without varicose veins to see how often the condition appears and how it changes over time. Participants get yearly checkups including ultrasound exams. The goal is to learn what factors make vein disease worse and how it naturally progresse…
Sponsor: Russian Phlebological Association • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC