Univentricular heart
MONDO:0015451Univentricular heart (UVH) is a severe congenital cardiac malformation characterized by both atria related entirely or almost entirely to one functionally single ventricular chamber. The clinical manifestations include congestive heart failure, failure to thrive, cyanosis, hypoxemia and neurodevelopmental disabilities.
Also known as: Double inlet left ventricle
23 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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New heart solution tested in Kids' surgery: could it offer better protection?
Disease control TerminatedThis study compares two solutions, Custodiol and Custodiol-N, used to protect the heart during surgery for children with congenital heart defects. About 100 children will receive one of the two solutions while on a heart-lung machine. The goal is to see which one is safer and bet…
Phase: PHASE2 • Sponsor: Dr. F. Köhler Chemie GmbH • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New app aims to ease Parents' stress over Baby's heart surgery decision
Symptom relief OngoingThis study tests whether a web-based decision aid app can reduce stress and improve decision-making for parents whose baby is diagnosed with a life-threatening congenital heart defect. 135 parents are randomly assigned to use the app alone or with an added values clarification ex…
Phase: NA • Sponsor: University of Utah • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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New biomarker study aims to improve outcomes for infants with rare heart condition
Knowledge-focused OngoingThis study measures certain substances in the blood (biomarkers) of infants with a rare heart defect called single-ventricle. The goal is to understand how these biomarkers relate to lung blood flow before and after a specific heart surgery (superior cavo-pulmonary anastomosis). …
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Heart defect study tracks kids' outcomes 11 years after surgery
Knowledge-focused OngoingThis study looks at 237 children born with hypoplastic left heart syndrome (HLHS), a serious heart defect. Researchers compare how well the heart works at age 11 in children who received one of two different shunts during their first surgery. The goal is to understand which shunt…
Sponsor: Carelon Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC