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Tourette syndrome

MONDO:0007661

A neurologic disorder caused by defective metabolism of the neurotransmitters in the brain. It is characterized by repeated involuntary movements (motor tics) and uncontrollable vocal sounds (vocal tics). The symptoms are usually manifested before the age of eighteen.

Also known as: Tourette disease, Tourette syndrome, Tourette's syndrome, motor-verbal tic disorder, GTS, Gilles De 50A Tourette syndrome, Gilles de la Tourette syndrome, Tourette disorder

53 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Psychiatric disorder (475) Mental disorder (249) Nervous system disorder (243) Hereditary disease (188) Brain disorder (131) Central nervous system disorder (115) Movement disorder (106) Syndromic disease (25) Tic disorder (21)
Trials to join now! 31 Not yet recruiting 3 Not yet finished but already full! 4 Completed 14 Terminated 1
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  • Brain pacemaker tested for uncontrollable tics

    Symptom relief Stopped early

    This study tested whether deep brain stimulation (DBS) could help people with severe Tourette syndrome whose symptoms don't improve with medication. Researchers placed tiny electrodes in a part of the brain called the thalamus to try to calm abnormal signals that cause tics. Only…

    Sponsor: Johns Hopkins University • Aim: Symptom relief

    Last updated Jun 27, 2026 09:00 UTC

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