Thyroid hormone metabolism, abnormal 1
MONDO:0800046A rare, genetic congenital hypothyroidism disorder characterized by mild global developmental delay in childhood, short stature, delayed bone age, and abnormal thyroid and selenium levels in serum (high total and free T4 concentrations, low T3, high reverse T3, normal to high TSH, decreased selenium). Intellectual disability, primary infertility, hypotonia, muscle weakness, and impaired hearing have also been reported.
Also known as: thyroid hormone metabolism, abnormal, THMA1, short stature-delayed bone age due to thyroid hormone metabolism deficiency
26 clinical trials for this condition and its sub-types.
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New MRI method may spot heart damage in thyroid patients without a needle
Diagnosis Not yet recruitingThis study will test whether a special MRI technique called T1 mapping can find and measure tiny scars in the heart muscle of people with long-term thyroid disease. The goal is to see if this non-invasive scan can replace the need for a heart biopsy. The study plans to enroll 40 …
Sponsor: Assiut University • Aim: Diagnosis
Last updated Jun 27, 2026 07:59 UTC
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Glow-in-the-Dark dye could save voices in thyroid surgery
Symptom relief Not yet recruitingThis phase 2 trial tests a dye called bevonescein that makes nerves glow during thyroid surgery, helping surgeons see and avoid them. Forty adults having thyroid removal will receive the dye before surgery. The main goal is to see if it improves voice outcomes by reducing nerve i…
Phase: PHASE2 • Sponsor: Matthew Spector • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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New study tests faster, less painful thyroid surgery technique
Symptom relief Not yet recruitingThis study compares two tools used during thyroid removal surgery: LigaSure and bipolar diathermy. The goal is to see which one leads to shorter surgery time, less pain, and fewer complications. Thirty adults having partial or total thyroid removal will take part.
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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AI eye in the OR: new model spots vital neck structures during thyroid surgery
Knowledge-focused Not yet recruitingThis study tests a computer vision model called PTAIR that helps surgeons identify parathyroid glands and recurrent laryngeal nerves during endoscopic thyroid surgery. About 100 adults with thyroid disease will take part. The model's ability to spot these structures will be compa…
Sponsor: Fujian Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Pesticide found in thyroid glands of caribbean patients
Knowledge-focused Not yet recruitingThis study will measure how much of the pesticide chlordecone is stored in the thyroid and nearby fat tissue of 69 adults having thyroid surgery in Guadeloupe. Researchers will also look at blood levels and ask about diet and job history to see what factors affect accumulation. T…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC