Thoracic aortic aneurysm
MONDO:0005396An aneurysm formed in the wall of the proximal portion of the descending aorta proceeding from the arch of the aorta.
78 clinical trials for this condition and its sub-types.
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New anchor device aims to secure aortic aneurysm repairs
Disease control CompletedThis registry tracked over 1,000 patients who received the Heli-FX EndoAnchor device during endovascular repair of aortic aneurysms. The device is designed to help hold the endograft in place and prevent leaks. Patients were followed for up to 5 years to see how safe and effectiv…
Sponsor: Medtronic Cardiovascular • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Tailored stents show promise for Hard-to-Treat aneurysms
Disease control CompletedThis study looked at 47 people with thoracoabdominal aortic aneurysms (a bulge in the main artery in the chest and belly). They received a custom-made stent graft (a fabric-covered metal tube) designed to fit their unique anatomy. The goal was to see if the aneurysm size stayed s…
Sponsor: JOTEC GmbH • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Heart surgery study seeks to pinpoint protection window
Knowledge-focused CompletedThis study looked at 80 adults having heart valve or aortic surgery to find out how long a special heart protection solution (Del Nido cardioplegia) keeps the heart safe during surgery. Researchers took blood samples at set times to see when heart injury began. The goal was to le…
Sponsor: Muhammet Talha Ceran, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Dye reveals hidden oxygen trouble in aortic aneurysms
Knowledge-focused CompletedThis study tested a dye called pimonidazole to see if it can safely detect low oxygen levels (hypoxia) in the aorta of people having surgery for an ascending aortic aneurysm. Nine adults received the dye before surgery, and researchers measured how much of it was in the removed a…
Phase: PHASE1 • Sponsor: Thomas Gleason • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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New monitoring methods aim to prevent paralysis after aortic surgery
Knowledge-focused CompletedThis study tests two new monitoring techniques—long loop reflexes (F-waves) and near-infrared spectroscopy (NIRS)—to detect spinal cord ischemia early after thoracoabdominal aortic aneurysm repair. Current methods work during surgery but are too painful for awake patients afterwa…
Sponsor: Maastricht University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC