Testicular disorder

This study tests proton beam therapy for stage II seminoma, a testicular cancer that is highly curable. The goal is to see if this more targeted radiation can treat the cancer effectively while reducing long-term side effects and the risk of developing another cancer later in lif…

This study tests a non-invasive light-based device (SR-NIRS) to measure blood flow and oxygen in the testicles of children. It includes 74 boys aged 1 month to 18 years, both healthy and those with sudden scrotal pain. The goal is to see if this device can help tell if testicular…

This study explores whether a liquid biopsy—a blood test that looks for tumor DNA and micro RNA—can detect and monitor testicular germ cell tumors. Researchers will collect blood samples from 200 men with stage I or metastatic testicular cancer at several time points during treat…

This study will test whether a thermal imaging camera can help doctors quickly diagnose the cause of acute testicular pain, especially testicular torsion, which requires urgent surgery. About 150 men with sudden testicular pain will have a thermal image taken in the emergency roo…

This study tests whether an artificial intelligence (AI) program can help doctors better diagnose testicular appendix torsion—a painful condition in boys that can look like other emergencies. Researchers will feed thousands of ultrasound images into the AI and compare its accurac…

This study tests an artificial intelligence algorithm called SiDTM v2.0 that helps embryologists choose the best sperm for a procedure called ICSI (a type of IVF). Currently, sperm selection is done by eye, which can vary between experts. The AI scores each sperm based on shape a…

This study tests whether a virtual support platform can improve emotional well-being in men who had testicular cancer in the last 5 years. 360 men in North Carolina will be split into two groups: one gets access to the support platform, the other gets educational materials only. …

This pilot trial tests whether adding emotional support to a cancer information website helps young adults (ages 20-39) with thyroid, melanoma, or testicular cancer feel less worried and distressed. 142 participants will either get general cancer info or the same info plus person…

This study tests whether a single hypnosis session during chemotherapy can reduce anxiety and other side effects like nausea in young people with cancer. It includes 70 participants aged 15-49 with sarcoma, germ cell tumors, or breast cancer. Researchers will compare anxiety leve…

This study tests a digital tool called TRANSCEND-XR that uses extended reality (like virtual reality) to help adolescents and young adults who have finished treatment for testicular cancer. The tool aims to teach them about long-term side effects, when to see a doctor, and how to…

This study is for young adults (ages 21-45) who had certain cancers as teens or young adults. Researchers are adapting a program that helps survivors manage their health after cancer treatment. The goal is to see if this program improves survivors' confidence and ability to handl…