Glowing dye could reveal hidden cancer spread in testicular tumors
NCT ID NCT07699640
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This trial investigates whether a minimally invasive procedure using a special dye can better detect cancer spread in men with early-stage testicular cancer. About 20-30% of these patients have cancer cells in lymph nodes that standard scans miss. Participants are randomly assigned to receive either standard surgery plus a dye-guided lymph node biopsy or standard surgery alone. The goal is to see if the dye-guided approach improves relapse-free survival and reduces unnecessary treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Indocyanine green (ICG) dye
- What this could lead to
- If successful, this approach could provide more accurate staging for early testicular cancer, helping to avoid unnecessary treatments while catching hidden spread earlier.
- What could go wrong
- This is a relatively early-stage trial with 171 participants, so results may not apply broadly. The procedure carries surgical risks, and the dye may not identify all affected lymph nodes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Asklepios Klinik Altona
Hamburg, Free and Hanseatic City of Hamburg, 22763, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Helios University Hospital Wuppertal
Wuppertal, North Rhine-Westphalia, 42283, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Helsinki University Hospital
Helsinki, 00014, Finland
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University Hospital Cologne
Cologne, North Rhine-Westphalia, 50937, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital Dresden
Dresden, Saxony, 01307, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital Düsseldorf
Düsseldorf, North Rhine-Westphalia, 40225, Germany
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University Hospital Marbug
Marburg, Hesse, 35043, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital Ulm
Ulm, Baden-Wurttemberg, 89081, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital Würzburg
Würzburg, Bavaria, 97080, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Turku
Turku, 20520, Finland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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