New chemo cocktail targets Hard-to-Treat testicular cancer

NCT ID NCT00183820

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This study tests a combination of three chemotherapy drugs—gemcitabine, oxaliplatin, and paclitaxel—in people with advanced testicular cancer that has not responded to standard cisplatin-based treatment or has returned after treatment. The goal is to see if this drug combination can shrink tumors or slow the disease. The trial enrolls about 30 adults with refractory germ cell tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gemcitabine, oxaliplatin, and paclitaxel

What this could lead to

If successful, this combination could offer a new treatment option for patients with testicular cancer that has stopped responding to standard chemotherapy.

What could go wrong

This is a small, early-phase study, so the combination may not prove effective enough for wider use. Chemotherapy side effects are expected and can be serious.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

germ cell tumor Neoplasms, Germ Cell and Embryonal testicular cancer testis refractory cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States