Temporal lobe epilepsy
MONDO:0005115A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see epilepsy, complex partial) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)
Also known as: epilepsy of temporal lobe, epilepsy, familial temporal lobe, familial temporal lobe epilepsy syndrome, temporal lobe epilepsy
38 clinical trials for this condition and its sub-types.
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Broader categories
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Routine EEGs may hold hidden clues to childhood epilepsy — a new analysis method is put to the test
Diagnosis CompletedThis study is testing whether a computer tool called BioEP can detect signs of seizure susceptibility in standard EEG recordings from children with epilepsy. Researchers will analyze past EEGs from 530 children aged 2 to 18 who already have an epilepsy diagnosis. The goal is to s…
Sponsor: Neuronostics Ltd • Aim: Diagnosis
Last updated Aug 01, 2026 00:00 UTC
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Zapping the brain to fight seizure blackouts: a new hope for epilepsy
Symptom relief CompletedThis study tested whether stimulating a deep brain area (the central thalamus) could help people with temporal lobe epilepsy stay conscious during seizures. Five participants received implanted electrodes that delivered stimulation when a seizure was detected. The goal was not to…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Scientists probe hidden memory system that might survive brain damage
Knowledge-focused CompletedThis completed study looked at how people learn and remember associations, like names or where you met someone. Researchers compared healthy young and older adults with patients who have memory problems from Alzheimer's or semantic dementia. They used memory tests and brain scans…
Phase: NA • Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Epilepsy study reveals hidden forgetfulness in navigation skills
Knowledge-focused CompletedThis study looked at how people with temporal lobe epilepsy (TLE) remember spatial information, like directions, compared to healthy volunteers. Researchers tested memory right after a navigation task and again six weeks later. They wanted to see if people with TLE forget spatial…
Phase: NA • Sponsor: Centre Hospitalier Metropole Savoie • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC