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Substernal goiter
MONDO:0006986An enlarged thyroid gland with at least 50% of the gland situated behind the sternum. It is an unusual presentation of an intrathoracic goiter. Substernal goiters frequently cause compression on the trachea leading to deviation, narrowing, and respiratory symptoms.
27 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New MRI method may spot heart damage in thyroid patients without a needle
Diagnosis Not yet recruitingThis study will test whether a special MRI technique called T1 mapping can find and measure tiny scars in the heart muscle of people with long-term thyroid disease. The goal is to see if this non-invasive scan can replace the need for a heart biopsy. The study plans to enroll 40 …
Sponsor: Assiut University • Aim: Diagnosis
Last updated Jun 27, 2026 07:59 UTC
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Glow-in-the-Dark dye could save voices in thyroid surgery
Symptom relief Not yet recruitingThis phase 2 trial tests a dye called bevonescein that makes nerves glow during thyroid surgery, helping surgeons see and avoid them. Forty adults having thyroid removal will receive the dye before surgery. The main goal is to see if it improves voice outcomes by reducing nerve i…
Phase: PHASE2 • Sponsor: Matthew Spector • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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New study tests faster, less painful thyroid surgery technique
Symptom relief Not yet recruitingThis study compares two tools used during thyroid removal surgery: LigaSure and bipolar diathermy. The goal is to see which one leads to shorter surgery time, less pain, and fewer complications. Thirty adults having partial or total thyroid removal will take part.
Phase: NA • Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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AI eye in the OR: new model spots vital neck structures during thyroid surgery
Knowledge-focused Not yet recruitingThis study tests a computer vision model called PTAIR that helps surgeons identify parathyroid glands and recurrent laryngeal nerves during endoscopic thyroid surgery. About 100 adults with thyroid disease will take part. The model's ability to spot these structures will be compa…
Sponsor: Fujian Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Pesticide found in thyroid glands of caribbean patients
Knowledge-focused Not yet recruitingThis study will measure how much of the pesticide chlordecone is stored in the thyroid and nearby fat tissue of 69 adults having thyroid surgery in Guadeloupe. Researchers will also look at blood levels and ask about diet and job history to see what factors affect accumulation. T…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC