Squamous cell neoplasm
MONDO:0002532A neoplasm that is composed of squamous epithelial cells. Squamous cell carcinoma is a representative example.
Also known as: epidermoid cell neoplasm, epidermoid cell tumor, epidermoid cell tumour, squamous cell neoplasm, squamous cell tumor, squamous cell tumor (qualifier value), squamous cell tumour, squamous cell tumour (qualifier value)
3179 clinical trials for this condition and its sub-types, 21 tagged with Squamous cell neoplasm itself.
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Sub-types of Squamous cell neoplasm
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Squamous cell carcinoma 177 trials · 1,774 incl. sub-types
39 sub-types
- Head and neck squamous cell carcinoma 831 trials · 1,057 incl. sub-types Sub-types →
- Esophageal squamous cell carcinoma 306 trials · 307 incl. sub-types Sub-types →
- Skin squamous cell carcinoma 151 trials · 158 incl. sub-types Sub-types →
- Squamous cell lung carcinoma 66 trials · 146 incl. sub-types Sub-types →
- Human papillomavirus-related squamous cell carcinoma 115 trials · 116 incl. sub-types Sub-types →
- Colorectal squamous cell carcinoma 1 trial · 54 incl. sub-types Sub-types →
- Adenosquamous carcinoma 8 trials · 45 incl. sub-types Sub-types →
- Cervical squamous cell carcinoma 36 trials · 40 incl. sub-types Sub-types →
- Metastatic squamous cell carcinoma 39 trials
- Squamous cell carcinoma of penis 21 trials · 29 incl. sub-types Sub-types →
- Vulvar squamous cell carcinoma 22 trials Sub-types →
- Squamous cell carcinoma of pancreas 3 trials · 13 incl. sub-types Sub-types →
- Bone squamous cell carcinoma 0 trials · 11 incl. sub-types Sub-types →
- Squamous carcinoma in situ 5 trials · 10 incl. sub-types Sub-types →
- Vaginal squamous cell carcinoma 8 trials
- Basaloid squamous cell carcinoma 2 trials · 5 incl. sub-types Sub-types →
- Bladder squamous cell carcinoma 5 trials Sub-types →
- Gastric squamous cell carcinoma 4 trials Sub-types →
- Papillary squamous carcinoma 1 trial · 4 incl. sub-types Sub-types →
- Thyroid gland squamous cell carcinoma 4 trials
- Endometrial squamous cell carcinoma 0 trials · 2 incl. sub-types Sub-types →
- Ovarian squamous cell carcinoma 2 trials
- Urethra squamous cell carcinoma 2 trials Sub-types →
- Keratinizing squamous cell carcinoma 0 trials · 1 incl. sub-types Sub-types →
- Pure squamous carcinoma of the urothelial tract 1 trial
- Scrotum squamous cell carcinoma 1 trial
- Squamous cell carcinoma of the small intestine 1 trial Sub-types →
- Ureter squamous cell carcinoma 1 trial
- Fallopian tube squamous cell carcinoma 0 trials
- Gallbladder squamous cell carcinoma 0 trials Sub-types →
- Prostate squamous cell carcinoma 0 trials Sub-types →
- Pseudoglandular squamous cell carcinoma 0 trials
- Renal pelvis squamous cell carcinoma 0 trials
- Sarcomatoid squamous cell carcinoma 0 trials Sub-types →
- Squamous cell breast carcinoma 0 trials Sub-types →
- Squamous cell carcinoma of liver and intrahepatic biliary tract 0 trials Sub-types →
- Squamous cell carcinoma of the corpus uteri 0 trials
- Thymus squamous cell carcinoma 0 trials Sub-types →
- Trachea squamous cell carcinoma 0 trials Sub-types →
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Squamous cell intraepithelial neoplasia 26 trials · 43 incl. sub-types
3 sub-types
- Cervical squamous intraepithelial neoplasia 28 trials
- Conjunctival intraepithelial neoplasm 0 trials
- Corneal intraepithelial neoplasm 0 trials
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Craniopharyngioma 29 trials
2 sub-types
- Adamantinous craniopharyngioma 5 trials
- Papillary craniopharyngioma 1 trial
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Vulvar squamous neoplasm 0 trials · 28 incl. sub-types
4 sub-types
- Vulvar squamous cell carcinoma 22 trials Sub-types →
- Vulvar intraepithelial neoplasia 5 trials · 6 incl. sub-types Sub-types →
- Vestibular papilloma 0 trials Sub-types →
- Vulvar seborrheic keratosis 0 trials Sub-types →
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Vaginal squamous tumor 0 trials · 8 incl. sub-types
2 sub-types
- Vaginal squamous cell carcinoma 8 trials
- Vaginal squamous papilloma 0 trials
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Ovarian squamous cell neoplasm 0 trials · 2 incl. sub-types
1 sub-type
- Ovarian squamous cell carcinoma 2 trials
Most studied deeper sub-types
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Could a probiotic help fight cancer? early trial launches
Disease control Recruiting nowThis early-stage trial is testing whether an oral probiotic called R-5780 is safe and tolerable when taken alongside a standard PD-1 checkpoint inhibitor in people with advanced solid tumors (like melanoma or certain skin cancers). About 33 adults whose cancer has not responded t…
Phase 1 • Sponsor: Rise Therapeutics LLC • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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New antibody combo aims to supercharge immune system against Hard-to-Treat cancers
Disease control Recruiting nowThis early-phase trial is testing an experimental drug called INBRX-106, alone or combined with the immunotherapy Keytruda, in people with advanced solid tumors (including lung, head and neck, melanoma, and others) that have stopped responding to standard treatments. The main goa…
Phase 1/2 • Sponsor: Inhibrx Biosciences, Inc • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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New radiation treatment shows promise for skin cancer in immunocompromised patients
Disease control Recruiting nowThis study tests a new type of radiation therapy called DaRT for people with a common skin cancer (squamous cell carcinoma) who have weakened immune systems. The treatment involves placing tiny radioactive seeds directly into the tumor to kill cancer cells from the inside. Resear…
Sponsor: Alpha Tau Medical LTD. • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New Antibody-Drug conjugate ZW251 enters first human trials for Hard-to-Treat cancers
Disease control Recruiting nowThis early-stage trial is testing a new drug called ZW251 in about 100 people with advanced solid tumors, including liver cancer (hepatocellular carcinoma), a type of lung cancer (squamous cell non-small cell lung cancer), and germ cell tumors. ZW251 is an antibody-drug conjugate…
Phase 1 • Sponsor: Zymeworks BC Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Glow-in-the-Dark dye could help surgeons spot hidden cancer cells
Diagnosis Recruiting nowThis early-stage trial tests a fluorescent dye attached to the cancer drug nivolumab. The dye is meant to make cancer cells glow during surgery, helping surgeons remove them more precisely. The study will enroll 40 people with head and neck cancer who are already scheduled for su…
Phase 1 • Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Diagnosis
Last updated Jul 09, 2026 00:00 UTC
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AI-Powered pocket microscope could revolutionize esophageal cancer detection
Diagnosis Recruiting nowThis study tests a portable microscope with artificial intelligence to help doctors spot early signs of esophageal cancer during a routine scope exam. Researchers will enroll 200 adults in Brazil and the United States who are already scheduled for screening. The goal is to see if…
Phase 2 • Sponsor: Baylor College of Medicine • Aim: Diagnosis
Last updated Jun 27, 2026 09:09 UTC