Squamous cell neoplasm
MONDO:0002532A neoplasm that is composed of squamous epithelial cells. Squamous cell carcinoma is a representative example.
Also known as: epidermoid cell neoplasm, epidermoid cell tumor, epidermoid cell tumour, squamous cell neoplasm, squamous cell tumor, squamous cell tumor (qualifier value), squamous cell tumour, squamous cell tumour (qualifier value)
3179 clinical trials for this condition and its sub-types, 21 tagged with Squamous cell neoplasm itself.
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Sub-types of Squamous cell neoplasm
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Squamous cell carcinoma 177 trials · 1,774 incl. sub-types
39 sub-types
- Head and neck squamous cell carcinoma 831 trials · 1,057 incl. sub-types Sub-types →
- Esophageal squamous cell carcinoma 306 trials · 307 incl. sub-types Sub-types →
- Skin squamous cell carcinoma 151 trials · 158 incl. sub-types Sub-types →
- Squamous cell lung carcinoma 66 trials · 146 incl. sub-types Sub-types →
- Human papillomavirus-related squamous cell carcinoma 115 trials · 116 incl. sub-types Sub-types →
- Colorectal squamous cell carcinoma 1 trial · 54 incl. sub-types Sub-types →
- Adenosquamous carcinoma 8 trials · 45 incl. sub-types Sub-types →
- Cervical squamous cell carcinoma 36 trials · 40 incl. sub-types Sub-types →
- Metastatic squamous cell carcinoma 39 trials
- Squamous cell carcinoma of penis 21 trials · 29 incl. sub-types Sub-types →
- Vulvar squamous cell carcinoma 22 trials Sub-types →
- Squamous cell carcinoma of pancreas 3 trials · 13 incl. sub-types Sub-types →
- Bone squamous cell carcinoma 0 trials · 11 incl. sub-types Sub-types →
- Squamous carcinoma in situ 5 trials · 10 incl. sub-types Sub-types →
- Vaginal squamous cell carcinoma 8 trials
- Basaloid squamous cell carcinoma 2 trials · 5 incl. sub-types Sub-types →
- Bladder squamous cell carcinoma 5 trials Sub-types →
- Gastric squamous cell carcinoma 4 trials Sub-types →
- Papillary squamous carcinoma 1 trial · 4 incl. sub-types Sub-types →
- Thyroid gland squamous cell carcinoma 4 trials
- Endometrial squamous cell carcinoma 0 trials · 2 incl. sub-types Sub-types →
- Ovarian squamous cell carcinoma 2 trials
- Urethra squamous cell carcinoma 2 trials Sub-types →
- Keratinizing squamous cell carcinoma 0 trials · 1 incl. sub-types Sub-types →
- Pure squamous carcinoma of the urothelial tract 1 trial
- Scrotum squamous cell carcinoma 1 trial
- Squamous cell carcinoma of the small intestine 1 trial Sub-types →
- Ureter squamous cell carcinoma 1 trial
- Fallopian tube squamous cell carcinoma 0 trials
- Gallbladder squamous cell carcinoma 0 trials Sub-types →
- Prostate squamous cell carcinoma 0 trials Sub-types →
- Pseudoglandular squamous cell carcinoma 0 trials
- Renal pelvis squamous cell carcinoma 0 trials
- Sarcomatoid squamous cell carcinoma 0 trials Sub-types →
- Squamous cell breast carcinoma 0 trials Sub-types →
- Squamous cell carcinoma of liver and intrahepatic biliary tract 0 trials Sub-types →
- Squamous cell carcinoma of the corpus uteri 0 trials
- Thymus squamous cell carcinoma 0 trials Sub-types →
- Trachea squamous cell carcinoma 0 trials Sub-types →
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Squamous cell intraepithelial neoplasia 26 trials · 43 incl. sub-types
3 sub-types
- Cervical squamous intraepithelial neoplasia 28 trials
- Conjunctival intraepithelial neoplasm 0 trials
- Corneal intraepithelial neoplasm 0 trials
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Craniopharyngioma 29 trials
2 sub-types
- Adamantinous craniopharyngioma 5 trials
- Papillary craniopharyngioma 1 trial
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Vulvar squamous neoplasm 0 trials · 28 incl. sub-types
4 sub-types
- Vulvar squamous cell carcinoma 22 trials Sub-types →
- Vulvar intraepithelial neoplasia 5 trials · 6 incl. sub-types Sub-types →
- Vestibular papilloma 0 trials Sub-types →
- Vulvar seborrheic keratosis 0 trials Sub-types →
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Vaginal squamous tumor 0 trials · 8 incl. sub-types
2 sub-types
- Vaginal squamous cell carcinoma 8 trials
- Vaginal squamous papilloma 0 trials
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Ovarian squamous cell neoplasm 0 trials · 2 incl. sub-types
1 sub-type
- Ovarian squamous cell carcinoma 2 trials
Most studied deeper sub-types
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New drug combo shows promise for tough head and neck cancers
Disease control CompletedThis phase 2 study tests whether adding the targeted drug Tarceva (erlotinib) to standard chemotherapy (cisplatin and docetaxel) can shrink tumors in people with head and neck cancer that has spread or returned. About 50 participants will receive the combination and be monitored …
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Experimental drug aims to supercharge immune system before cancer surgery
Disease control CompletedThis early-phase study tested a single dose of an experimental antibody (MEDI0562) given before surgery to 13 patients with advanced head and neck cancer or melanoma. The goal was to see if the drug safely activates the immune system to fight the cancer. Researchers compared givi…
Phase 1 • Sponsor: Providence Health & Services • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Double-Drug attack shows promise for tough head and neck cancers
Disease control CompletedThis study tested whether combining two FDA-approved cancer drugs, cetuximab and nivolumab, could help people with advanced head and neck cancer that has returned or spread. A total of 95 participants received the drug combination to find the best dose and see if it improves surv…
Phase 1/2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Experimental vaccines show promise against HPV-Driven cancers
Disease control CompletedThis completed phase I/II trial tested two experimental vaccines, HB-201 and HB-202, in 198 people with HPV 16+ cancers. The goal was to find a safe dose and see if the vaccines could shrink tumors. Participants received the vaccines alone or with standard treatments like pembrol…
Phase 1/2 • Sponsor: Hookipa Biotech GmbH • Aim: Disease control
Last updated Jun 26, 2026 17:14 UTC
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DNA risk report may nudge people to shield from sun
Prevention CompletedThis study looked at whether giving people personalized information about their genetic risk for melanoma could encourage them to protect themselves from the sun. Over 2,000 adults received either standard sun safety tips or tailored advice based on their DNA. Researchers then tr…
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Prevention
Last updated Jun 27, 2026 08:05 UTC
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Real-world data on keytruda and opdivo for HPV throat cancer could shape future trials
Knowledge-focused CompletedThis study looked at 662 patients with HPV-positive throat cancer that had spread or come back. Researchers wanted to see how patients were treated with pembrolizumab (Keytruda) or nivolumab (Opdivo), with or without chemotherapy, in real-world settings. The goal was to gather in…
Sponsor: Hookipa Biotech GmbH • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:18 UTC