Spondyloepimetaphyseal dysplasia, matrilin-3 type

MONDO:0012108

A spondyloepimetaphyseal dysplasia characterized by disproportionate early-onset dwarfism, bowing of the lower limbs, short, wide and stocky long bones with severe epiphyseal and metaphyseal changes, lumbar lordosis, hypoplastic iliac bones, flat ovoid vertebral bodies and normal hands.

Also known as: SEMD, MATN3-related, SEMD, matrilin-3 type, spondyloepimetaphyseal dysplasia, Borochowitz-Cormier-Daire type, SEMD MATN3-related, spondyloepimetaphyseal dysplasia matrilin-3 related, spondyloepimetaphyseal dysplasia matrilin-3 type, spondyloepimetaphyseal dysplasia, matrilin-3 related

35 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Musculoskeletal system disorder (196) Hereditary disease (172) Bone disorder (47) Human disease (14) Osteochondrodysplasia (12) Skeletal system disorder (4) Bone development disease (2) Disease of genetic or genomic mechanism (2) Skeletal dysplasia (1)

Trials to join now! 17 Not yet recruiting 6 Not yet finished but already full! 4 Completed 7 Terminated 1

Scientists gather leftover surgical tissue to unlock secrets of bone disease

Knowledge-focused Terminated

This study collected bone, cartilage, skin, and fat tissue from 50 patients undergoing surgery at Children's National Medical Center. The goal was to grow cells from these tissues in the lab and analyze them to better understand bone and connective tissue diseases. The study was …

Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused

Last updated Jun 27, 2026 07:52 UTC

Spondyloepimetaphyseal dysplasia, matrilin-3 type

Broader categories

Scientists gather leftover surgical tissue to unlock secrets of bone disease