Spondylocostal dysostosis
MONDO:0000359Spondylocostal dysplasia is a rare genetic disorder characterized by defects of the bones of the spine (vertebrae) and abnormalities of the ribs. Ribs can be fused or missing in chaotic patterns. These malformations are present at birth (congenital).
Also known as: Spondylocostal Dysplasia, costovertebral dysplasia, spondylocostal dysostosis, spondylocostal dysplasia, Jarcho-Levin syndrome, SCD, SCDO
25 clinical trials for this condition and its sub-types.
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Broader categories
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Spinal implants pass 24-Month safety check in 77 patients
Disease control CompletedThis study followed 77 adults who received spinal implants (PASS LP, PASS DEGEN, or PASS TULIP PRIME) to treat degenerative spine conditions like disc degeneration or spinal deformity. The main goal was to see if the bones fused properly after 24 months. Researchers also tracked …
Sponsor: Medicrea International • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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App-based therapy shows promise in preventing chronic pain after teen spinal surgery
Symptom relief CompletedThis study tested a mobile app called SurgeryPal that teaches teens coping skills before and after major spine surgery. 433 teens aged 12-18 were randomly assigned to use the app or receive standard education. The goal was to see if the app could reduce pain and prevent pain from…
Phase: NA • Sponsor: Seattle Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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New Ultrasound-Guided injection technique tested for back pain relief
Symptom relief CompletedThis pilot study tested whether using ultrasound to guide pharmacopuncture (herbal injections) is safe and effective for neck and back pain. Fifty adults with spinal disorders received the treatment, and researchers tracked side effects, pain levels, disability, and quality of li…
Sponsor: Jaseng Medical Foundation • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Spine surgery Patients' data collected to improve future care
Knowledge-focused CompletedThis study gathered information from 193 adults who had surgery or orthopedic treatment for spine problems. Researchers collected clinical, functional, and social data to create a detailed database. The goal was to better understand patient outcomes and standardize how data is co…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Spine scan showdown: MRI vs PET/CT – safety and clarity compared
Knowledge-focused CompletedThis study looked at 120 adults with neck or lower back spine issues to compare two types of scans: contrast-enhanced MRI and FDG-PET/CT. Researchers checked how clear the images were and whether the scans caused any short-term changes in kidney function or blood counts. The goal…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:08 UTC
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New 3D X-Ray technique maps body alignment in posture disorders
Knowledge-focused CompletedThis completed study looked at how the skeleton is aligned with gravity in adults with postural problems. Researchers used a low-dose X-ray device called EOS to create 3D images of the spine and pelvis. The goal was to better understand the body's geometry in people with balance …
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Ketone supplement shows promise for brain fog in early memory loss
Knowledge-focused CompletedThis pilot study tested whether a single dose of an oral ketone supplement could increase blood flow and improve brain connectivity in 15 older adults with subjective or mild cognitive decline. Participants had one 2-hour session including MRI scans and cognitive tests. The goal …
Phase: NA • Sponsor: University Department of Geriatric Medicine FELIX PLATTER • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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New device aims to cut spine screw errors in half
Knowledge-focused CompletedThis study tested a new lightweight device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Fourteen adults having spine surgery used the device to guide screw placement. The goal was to see if the device reduces screw misplacement and is safe…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Massive spine surgery database aims to unlock better treatments
Knowledge-focused CompletedThis study collected information from over 8,000 people who had spine surgery for conditions like degeneration, deformity, or trauma. Researchers gathered X-ray and health data to learn which treatments work best for different patients. The goal was to build a database to answer …
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Routine x-rays after spinal fusion may be unnecessary, study suggests
Knowledge-focused CompletedThis study reviewed the records of 978 adults who had spinal fusion surgery to see how often routine follow-up X-rays led to additional tests or changes in treatment. The goal is to find out whether these X-rays are truly helpful or if they can be skipped. The results could help …
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC