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Skin basal cell carcinoma
MONDO:0005341The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas.
Also known as: BCC, basal cell cancer, basal cell carcinoma, basal cell tumor, basal cell tumour, basal cell tumour (morphologic abnormality), malignant basal cell tumour, malignant basal cell tumour (morphologic abnormality)
2830 clinical trials for this condition and its sub-types, 52 tagged with Skin basal cell carcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Skin basal cell carcinoma
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Nodular basal cell carcinoma 8 trials
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Basosquamous carcinoma 1 trial
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Morpheaform basal cell carcinoma 1 trial
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Adamantinoid basal cell epithelioma 0 trials
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Anal margin basal cell carcinoma 0 trials
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External ear basal cell carcinoma 0 trials
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Follicular basal cell carcinoma 0 trials
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Metatypical basal cell carcinoma 0 trials
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Micronodular basal cell carcinoma 0 trials
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Penis basal cell carcinoma 0 trials
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Sarcomatoid basal cell carcinoma 0 trials
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Scrotum basal cell carcinoma 0 trials
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Sebaceous basal cell carcinoma 0 trials
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Signet ring basal cell carcinoma 0 trials
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Skin adenoid basal cell carcinoma 0 trials
1 sub-type
- Cervical adenoid basal carcinoma 0 trials
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Skin clear cell basal cell carcinoma 0 trials
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Skin cystic basal cell carcinoma 0 trials
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Skin pigmented basal cell carcinoma 0 trials
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Vulva basal cell carcinoma 0 trials
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Cancer-Fighting virus teams up with immunotherapy to tackle rare skin tumors
Disease control OngoingThis phase II trial is testing whether a combination of talimogene laherparepvec (a modified herpes virus that infects and kills cancer cells) and nivolumab (an immunotherapy drug) can shrink tumors in people with rare skin cancers or lymphomas that haven't responded to standard …
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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New hope for kidney transplant patients with cancer: drug combo aims to fight tumors without losing the donated kidney
Disease control OngoingThis early-stage study tests whether a mix of three drugs—tacrolimus, nivolumab, and ipilimumab—can shrink or control certain skin cancers in people who have had a kidney transplant. The main goal is to see if the cancer responds without causing the body to reject the transplante…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Immune cells injected into skin tumors show promise in early trial
Disease control OngoingThis early-phase trial tests whether injecting special immune cells (natural killer cells) directly into skin cancer tumors can safely kill cancer cells. The study compares two types of donor NK cells—standard ones and ones engineered to be more potent—in 40 patients with basal o…
Early phase 1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Elderly skin cancer patients may skip surgery: study tests 'Watch and Wait'
Disease control OngoingThis study looks at whether active surveillance (watching the cancer without treating it right away) is a safe and comfortable choice for people aged 65 and older who have a low-risk type of skin cancer called basal cell carcinoma. The cancer is slow-growing and unlikely to sprea…
Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Could immunotherapy before surgery spare facial features in skin cancer?
Disease control PausedThis phase 2 trial is testing whether giving immunotherapy drugs (cemiplimab alone or with fianlimab) before surgery can shrink advanced basal cell carcinoma of the head and neck. The goal is to make surgery less extensive, preserving important structures like the eye, nose, or l…
Phase 2 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Could taking breaks from skin cancer drug keep it working?
Disease control OngoingThis trial tests a new way of taking the drug sonidegib for people with advanced basal cell carcinoma that cannot be surgically removed. Instead of taking the drug continuously, patients who have already achieved a complete response will take it in cycles with breaks (14 days on/…
Phase 2 • Sponsor: Gruppo Oncologico del Nord-Ovest • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Blue dye cream takes on tough skin cancer in new trial
Disease control By invitation onlyThis study tests a cream made from methylene blue, a common dye, on people with advanced basal cell carcinoma (a type of skin cancer) that cannot be treated with surgery or radiation. Twenty adults will apply the cream to their tumors every two days for one month. Researchers wil…
Phase 3 • Sponsor: Daryoush Hamidi Alamdari, PhD • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Can a simple blood test predict skin cancer outcomes?
Knowledge-focused OngoingThis study looks at blood samples from 20 adults with melanoma or other skin cancers to see if certain markers in the blood can predict how well treatment works or how long someone lives. Researchers will compare these markers to standard measures like tumor response and survival…
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Danish study checks skin cancer patients years after radiation
Knowledge-focused By invitation onlyThis study invites 2,900 adults who had radiotherapy for non-melanoma skin cancer on the head or neck between 2020 and 2024 to a follow-up visit at least two years later. Participants will fill out a questionnaire about how the treated area looks and have their skin examined. The…
Sponsor: University of Aarhus • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC