Sensory peripheral neuropathy
MONDO:0002321Inflammation or degeneration of the sensory nerves.
Also known as: peripheral neuropathy of sensory nerve, peripheral sensory neuropathy, sensory nerve peripheral neuropathy
51 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Drug combo aims at genetic weaknesses in head and neck cancer
Disease control CompletedThis early-stage trial tested a combination of two oral drugs, tipifarnib and alpelisib, in 45 adults with recurrent or metastatic head and neck squamous cell carcinoma that has specific genetic changes (HRAS overexpression or PIK3CA mutations). The goal was to find a safe dose a…
Phase: PHASE1, PHASE2 • Sponsor: Kura Oncology, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New drug combo shows promise for Hard-to-Treat breast cancer
Disease control CompletedThis study tested a drug called alpelisib combined with hormone therapy (fulvestrant or letrozole) in 383 people with advanced breast cancer that has a specific genetic change (PIK3CA mutation). The goal was to see how many patients were alive without their cancer getting worse a…
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New drug cocktail targets tough lung cancer mutation
Disease control CompletedThis phase 2 trial tested a combination of two oral drugs, RMC-4630 and sotorasib, in 47 adults with advanced KRASG12C-mutant non-small cell lung cancer that had progressed after standard treatments. The goal was to see if the combination could shrink tumors. The study is now com…
Phase: PHASE2 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Laser test could objectively measure nerve pain for first time
Diagnosis CompletedThis study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…
Phase: NA • Sponsor: University of Utah • Aim: Diagnosis
Last updated Jun 27, 2026 12:09 UTC
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New blood test could replace painful biopsies for breast cancer patients
Diagnosis CompletedThis study tested a new blood test (liquid biopsy) that looks for cancer DNA in the blood of 30 women with advanced ER+/HER2- breast cancer. The goal was to see if the test can accurately find cancer mutations without needing a traditional tissue biopsy. The results will help doc…
Sponsor: Pharmassist Ltd • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC
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Ultrasound may spot rare nerve disease CANVAS
Diagnosis CompletedThis study tested whether ultrasound of the nerves can help diagnose CANVAS, a rare genetic disorder that causes balance problems, nerve damage, and dizziness. Researchers measured nerve size in 35 people with confirmed CANVAS and compared them to healthy individuals. The goal wa…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Diagnosis
Last updated Jun 27, 2026 08:01 UTC
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New hope for HIV nerve pain: Drug-Free relief on the horizon?
Symptom relief CompletedThis study tested new non-drug treatments to reduce nerve pain in the feet and legs of people with HIV. 161 adults with HIV-related nerve pain tried these approaches to see if they could ease pain and improve quality of life. The goal was to find better ways to manage this common…
Phase: NA • Sponsor: New York University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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New drug tracking study offers no cure, but key insights for future cancer treatments
Knowledge-focused CompletedThis study looked at how the drug tuvusertib is absorbed, broken down, and removed from the body in 12 people with advanced solid tumors. Participants received a tiny radioactive tracer to track the drug. The main goal was to understand the drug's path in the body, not to treat t…
Phase: PHASE1 • Sponsor: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Age matters: study measures exact ciprofol dose for loss of consciousness
Knowledge-focused CompletedThis completed study looked at 125 patients of different ages to find out how much ciprofol (an anesthetic drug) they needed to lose consciousness. Researchers measured the dose and brain activity (bispectral index) during anesthesia induction. The goal is to help doctors tailor …
Sponsor: General Hospital of Ningxia Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New registry sheds light on rare overgrowth diseases
Knowledge-focused CompletedThis completed study created a French national registry for people with rare overgrowth syndromes caused by PIK3CA gene mutations. Researchers collected medical and genetic information from 28 patients to better understand these conditions and estimate how many people are affecte…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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French hospital data reveals hidden burden of rare PROS disorders
Knowledge-focused CompletedThis study looked at hospital records from 2015 to 2022 to find out how many people in France have a group of rare genetic conditions called PROS. Researchers counted new cases each year, described patient ages and other health problems, and estimated costs. No treatments were te…
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC