Sciatica
MONDO:0024333A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of sciatic neuropathy; radiculopathy (involving the spinal nerve roots; L4, L5, S1, or S2, often associated with intervertebral disk displacement); or lesions of the cauda equina.
Also known as: bilateral sciatica, bilateral sciaticas, neuralgia, sciatic, neuralgias, sciatic, sciatic Neuralgias, sciatic neuralgia, sciatica, bilateral
75 clinical trials for this condition and its sub-types.
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Broader categories
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Can a mild zapping of skin nerves unlock the secrets of chronic pain?
Knowledge-focused Stopped earlyThis study is testing a mild electrical stimulation method on the skin to better understand nerve pain in people with neuropathy or chronic pain after surgery. Researchers will measure how pain intensity and thresholds change. The goal is to learn more about how pain signals work…
Sponsor: Swiss Paraplegic Research, Nottwil • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Could a simple blood test track nerve damage? a study investigates NT-3 levels in neuropathy.
Knowledge-focused Stopped earlyThis study measures levels of a protein called NT-3 in the blood of people with peripheral neuropathy or Charcot-Marie-Tooth disease. Researchers will compare these levels with measures of muscle strength, mobility, and daily function. The goal is to see whether NT-3 levels corre…
Sponsor: Zarife Sahenk • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Spine scanner study ends early after just one patient
Knowledge-focused Stopped earlyThis study tested a new 3D scanning device that aims to help surgeons match a patient's spine bones to their MRI or CT scans during surgery. The goal was to see if the scanner could accurately and consistently map the spine to improve surgical precision. Only one person took part…
Sponsor: Advanced Scanners Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC