Schistosomiasis
MONDO:0015254An infectious disease caused by parasitic trematodes of the genus Schistosoma that colonize human blood vessels and release eggs that can cause granulomatous reactions leading to acute (swimmer's itch or acute schistosomiasis syndrome) or chronic disease. Depending on where the eggs lodge, manifestations of chronic schistosomiasis can include diarrhea, abdominal pain, loss of appetite, anemia (intestines), hepatosplenism, periportal fibrosis with portal hypertension (liver), urogenital inflammation and scarring, hematuria and dysuria (genitourinary system). Other patients may be asymptomatic.
Also known as: Bilharzia, bilharziasis, schistosomiasis, snail fever
43 clinical trials for this condition and its sub-types.
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Broader categories
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Which antibiotic combo is safer for your kidneys? new trial aims to find out
Disease control Not yet recruitingThis study compares two common antibiotic combinations—vancomycin with piperacillin/tazobactam versus vancomycin with meropenem—to see which is less harmful to the kidneys. About 852 hospitalized adults with serious infections will be randomly assigned to one of the two combos. T…
Phase: PHASE4 • Sponsor: Bassett Healthcare • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New study eyes selexipag for neglected form of lung hypertension
Disease control Not yet recruitingThis study looks at how well the oral medication selexipag works over the long term for people with a specific type of lung hypertension caused by schistosomiasis (a parasitic infection). Researchers will compare patients who received selexipag as part of routine care to similar …
Sponsor: Caio Júlio César dos Santos Fernandes • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Simple urine test could revolutionize schistosomiasis detection
Diagnosis Not yet recruitingThis study aims to develop a new urine test for schistosomiasis, a parasitic infection. Researchers will test a nanobody-based strip on 2500 participants, comparing it to the standard microscope method. If accurate, it could offer a quick, non-invasive diagnostic tool.
Sponsor: Pemba Ministry of Health Zanzibar • Aim: Diagnosis
Last updated Jun 27, 2026 12:03 UTC
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Worldwide ICU infection snapshot aims to save lives
Knowledge-focused Not yet recruitingThis observational study will look at 10,000 adults in intensive care units (ICUs) around the world during a single 24-hour period. Researchers want to find out how common infections and antibiotic-resistant bacteria are, how they are treated, and how patients recover. No new tre…
Sponsor: Universidad de la Sabana • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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23,000 seniors join study to unlock secrets of aging and infection
Knowledge-focused Not yet recruitingThis research project aims to understand why older adults get more infections and why those infections can be more serious. By following 23,000 people aged 60 and older, scientists will collect health data and samples like blood and stool to study how the immune system changes wi…
Sponsor: Huashan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Egyptian schistosomiasis study launches to map disease hotspots
Knowledge-focused Not yet recruitingThis study will measure how many people in Assiut Governorate, Egypt, have schistosomiasis, a parasitic disease. Researchers will test urine and stool samples from 359 participants and ask about risk factors. The goal is to better understand the current burden of the disease in t…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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30,000 blood samples could revolutionize rapid disease testing
Knowledge-focused Not yet recruitingThis study will collect blood samples from 30,000 adults in the UK with various health conditions, including blood clots, infections, heart disease, diabetes, and more. The samples will be used to develop and fine-tune new diagnostic tests for the cobas® lumira device, which allo…
Sponsor: LumiraDx UK Limited • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Can the Body's own 'Off Switch' for inflammation predict who survives severe infection?
Knowledge-focused Not yet recruitingThis study will follow 300 adults with severe infections in the ICU to see how levels of specialized pro-resolving mediators (SPMs)—natural molecules that help stop inflammation—change over time. Researchers will use blood samples already collected during routine care, so no extr…
Sponsor: Second Affiliated Hospital of Wenzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC