Root caries

This study compares two treatments for severely damaged lower molars: a tooth-saving surgery called hemisection (removing the damaged root) versus replacing the whole tooth with a dental implant. Researchers will track 28 participants over 12 months to see which option leads to b…

This study compares two treatments for severely damaged upper molars: root amputation (removing only the damaged root and keeping the rest of the tooth) versus replacing the whole tooth with a dental implant. Researchers will track pain, bone healing, and implant stability over 1…

This study tests whether a robot can place dental implants more accurately than a computer-guided navigation system in the front upper jaw. Twenty-four adults needing an implant will be randomly assigned to one of the two methods. The main goal is to see which approach achieves b…

This study compares two dental filling materials for cavities that form near the gum line (cervical lesions). One is a self-hardening composite, the other a flowable composite. Fifty adults will receive one of the two fillings and be checked over 18 months to see which stays in p…

This study tests a new type of tooth filling that sticks to the tooth without needing a separate bonding step. Researchers will compare it to the standard filling method in 75 adults with small to moderate cavities near the gum line. The fillings will be checked over 18 months fo…

This study tests whether different fluoride treatments—like varnishes, solutions, and mousse—can stop root cavities from getting worse in adults over 44. About 136 participants in Switzerland will use these products at home or get them applied by a dentist twice a year. The goal …

This study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. T…

This early-phase trial will test four orthobiologic treatments—PRP, bone marrow concentrate, hyaluronic acid, and nanofat—in 300 adults with various muscle, joint, tendon, or bone conditions. The goal is to see if these natural substances can reduce pain and improve joint functio…

This study looks at whether a mobile app can help people with common pains (neck, shoulder, back, or knee) do their prescribed home exercises more regularly. About 30 adults will be split into two groups: one using the app and one doing traditional exercises. The goal is to see i…

This study aims to translate and adapt a widely used questionnaire for musculoskeletal problems into Urdu. Researchers will enroll 110 Urdu-speaking adults, including patients with muscle or joint issues and healthy volunteers. The goal is to create a validated tool to measure sy…

This study looks at how patients feel when reading their own medical notes. Some will read the original doctor's note, others will read a simpler version written by artificial intelligence. Researchers want to see if the AI summary changes how much patients trust their doctor or …

This study tests a decision support system called SmaRTWork to help people on sick leave due to muscle or back pain return to work. About 298 adults in Norway will either use the system or receive usual care. The main goal is to see if the tool helps them return to work sustainab…