Rhegmatogenous retinal detachment

This early-stage study tests whether an injection of the drug topotecan into the eye can safely prevent retinal detachment from coming back in people with a condition called proliferative vitreoretinopathy (PVR). About 50 adults having retinal detachment surgery will either recei…

This study tests whether using sterile air during eye surgery for a detached retina works as well as the standard gas bubble. About 150 patients from 10 UK centers will be randomly assigned to receive either air or a fluorinated gas. The main goal is to see if the retina stays re…

This study will test a new, noninvasive camera called XyCAM CRE that measures blood flow in the back of the eye. Researchers will compare its images with standard eye tests in 350 adults with retinal disorders. The goal is to see if this camera can provide extra information to he…

This study will enroll 50 adults with a specific type of retinal detachment to look for clues in eye fluid and images that might predict a complication called PVR. Participants will receive standard surgery plus extra non-invasive eye scans and a sample of their eye fluid taken d…

This study tests whether short animated videos, available in 25 languages, can help people with retinal detachment understand their condition and surgery better. 600 adults will either get standard counselling or counselling plus a video in their preferred language. Researchers w…