Relapsing polychondritis
MONDO:0019125A rare, clinically heterogeneous, multisystemic inflammatory disease characterized by inflammation of the cartilage and proteoglycan rich structures leading to cartilage damage with joint, ocular and cardiovascular involvement.
Also known as: chronic atrophic polychondritis, recurrent polychondritis
14 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New hope for rare cartilage disease: five drugs put to the test
Disease control Recruiting nowThis study tests five different standard immune-suppressing drugs to see which works best for controlling relapsing polychondritis, a rare disease that causes painful inflammation of cartilage. About 20 adults will receive one of the drugs and be monitored for 26 weeks. The goal …
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Vitamin E-Infused hip implants face off against ceramic in wear test
Disease control Recruiting nowThis study compares two types of hip replacement materials in 100 adults aged 18 to 65 who need a total hip replacement. One group gets a ceramic-on-polyethylene implant where the polyethylene is infused with vitamin E to reduce wear. The other group gets a standard ceramic-on-ce…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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New study aims to ease pain after hip replacement
Symptom relief Recruiting nowThis study tests two ways to manage pain after hip replacement surgery. One group gets a nerve block plus a second nerve block; the other gets a nerve block plus wound numbing. The goal is to see which method reduces pain and the need for opioid painkillers. About 102 adults havi…
Phase: NA • Sponsor: Ospedale Edoardo Bassini • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Massive study aims to unlock mysteries of rare blood vessel disease
Knowledge-focused Recruiting nowThis study follows up to 4,000 people with vasculitis (a group of diseases that cause blood vessel inflammation) and healthy volunteers over many years. Researchers collect blood, urine, imaging, and genetic samples to learn how the disease develops and changes. The goal is to fi…
Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) • Aim: Knowledge-focused
Last updated Aug 18, 2026 03:00 UTC
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Hip replacement patients monitored for years to improve future surgeries
Knowledge-focused Recruiting nowThis study will follow 200 people who have had a complex or revision hip replacement at University Hospitals Leuven. The goal is to track how many need another surgery and why, and to improve care by learning from real-world results. No new treatment is being tested—this is an ob…
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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New study aims to unravel rare cartilage disease
Knowledge-focused Recruiting nowThis study follows 100 people with relapsing polychondritis, a rare disease that causes repeated inflammation of cartilage in the ears, nose, and airways. Researchers will collect medical history and survey data to learn how the disease develops. The goal is to better understand …
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Which knee implant gets you back in the game? new study aims to find out.
Knowledge-focused Recruiting nowThis study looks at how often people can return to sports at least three years after total knee replacement. It compares three different types of knee prostheses to see if one type leads to better sports participation. The study will include 660 adults who had their first knee re…
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC