Raynaud disease
MONDO:0008364An episodic vasoconstriction resulting in discoloration of the skin and pain in the affected areas, often involving fingers or toes. Classically associated with triphasic color changes (white, blue, red) but may be biphasic. Often occurs in response to cold temperatures or emotional stress. May be primary or secondary to an underlying autoimmune disease.
Also known as: Raynaud disease, Raynaud syndrome, Raynaud's disease, Raynaud's syndrome, Raynaud's syndrome (disorder) [ambiguous], secondary Raynaud disease, secondary Raynaud phenomenon, secondary Raynaud's disease
155 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Heart drug tested to fight COVID-19 complications
Disease control TerminatedThis study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…
Phase: PHASE2, PHASE3 • Sponsor: Cardiol Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Painkiller showdown: which is safer for the heart?
Knowledge-focused TerminatedThis study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…
Phase: PHASE4 • Sponsor: Platelet and Thrombosis Research, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Ear zaps may reveal nerve secrets
Knowledge-focused TerminatedThis study looked at how stimulating the ear with mild electrical pulses affects the body's automatic functions, like blood flow and temperature. Ten healthy volunteers had their skin temperature measured after ear stimulation. The goal was to understand if precise ear points mat…
Phase: NA • Sponsor: Hôpital Européen Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC