Radioulnar synostosis-developmental delay-hypotonia syndrome
MONDO:0009952Radioulnar synostosis-developmental delay-hypotonia syndrome, also known as Der Kaloustian-McIntosh-Silver syndrome, is an extremely rare syndrome with synostosis described in about 4 patients to date with clinical manifestations including congenital unilateral radioulnar synostosis, generalized hypotonia, developmental delay, and dysmorphic facial features (long face, prominent nose and ears).
Also known as: Der Kaloustian-McIntosh-Silver syndrome, radioulnar synostosis with developmental delay and hypotonia syndrome, der Kaloustian mcintosh silver syndrome, radioulnar synostosis, unilateral, with developintellectual disability and hypotonia, radioulnar synostosis, unilateral, with developmental retardation and hypotonia, unilateral radio-ulnar synostosis, generalised hypotonia, developintellectual disability, and a characteristic facial appearance, unilateral radio-ulnar synostosis, generalised hypotonia, developmental retardation, and a characteristic facial appearance, unilateral radio-ulnar synostosis, generalized hypotonia, developintellectual disability, and a characteristic facial appearance
18 clinical trials for this condition and its sub-types.
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Cannabinoid drug tested for aggression in disabled adults
Symptom relief CompletedThis early-phase trial tested the safety of nabilone, a synthetic cannabinoid, in 20 adults with intellectual and developmental disabilities who have severe aggression. The goal was to see if the drug is well-tolerated and to gather initial data on whether it might reduce aggress…
Phase: PHASE1 • Sponsor: Hsiang-Yuan Lin • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Kids test new bionic foot design
Knowledge-focused CompletedThis study tested a new prosthetic foot for children with leg amputations or birth defects. Thirteen kids walked with the device and gave feedback on stiffness and performance. The goal was to gather ideas to improve future foot designs.
Sponsor: Össur Iceland ehf • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Paws for thought: cat training program shows promise for youth with disabilities
Knowledge-focused CompletedThis study tested a new program where early adolescents with developmental disabilities learned to train their family cat using positive reinforcement. The goal was to see if the training could improve the cat's attachment to the child and give the child a sense of responsibility…
Phase: NA • Sponsor: Oregon State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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New program aims to boost tech careers for young adults with disabilities
Knowledge-focused CompletedThis study tested a program called TECH-Prep designed to help African American high school students and young adults with developmental disabilities explore careers in technology. The program included training and internships to increase interest in tech jobs, confidence, and rea…
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Which toothbrush works best for kids with special needs? study finds out!
Knowledge-focused CompletedThis study tested whether a triple-headed toothbrush removes more dental plaque than a regular single-headed toothbrush when parents brush the teeth of preschool children with developmental disabilities. Twenty-four children aged 3 to 6 years participated, and each child tried bo…
Phase: NA • Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC