Quadriplegia
MONDO:0001590Paralysis of all four limbs.
Also known as: bilateral diplegia, tetraplegia
59 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Surgery may give paralyzed patients a helping hand
Disease control OngoingThis study tests whether nerve transfer surgery can improve arm and hand function in people with complete spinal cord injuries who have no hand movement. Seventy participants will undergo surgery followed by 48 months of occupational therapy. The goal is to help them regain indep…
Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Nasal gene therapy offers new hope for brain injury patients
Disease control ENROLLING_BY_INVITATIONThis study follows 25 people aged 2 to 65 with cerebral palsy or brain damage from lack of oxygen who have already received a new gene therapy given as a nose spray. The therapy delivers 15 genes meant to repair the brain, reduce inflammation, and improve movement and thinking. R…
Sponsor: Healing Hope International • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Bionic hand control gives new grip to paralyzed patients
Disease control OngoingThis study tests an implanted stimulator and sensor that helps people with cervical spinal cord injury regain hand and arm function. Ten participants will use the device to perform everyday tasks like grasping objects. The goal is to improve independence and quality of life.
Phase: NA • Sponsor: MetroHealth Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Own stem cells infused in spinal cord injury hope
Disease control NO_LONGER_AVAILABLEThis expanded access program gives one patient with a spinal cord injury at the C5-C7 level a single infusion of their own stem cells (HB-adMSCs). The stem cells are taken from the patient's fat tissue and grown in a lab before being given back. The goal is to see if this approac…
Sponsor: Hope Biosciences LLC • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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AI boosts brain scan accuracy in massive new trial
Diagnosis ENROLLING_BY_INVITATIONThis study tests whether an AI tool can help radiologists read brain CT and MRI scans more accurately and quickly. Researchers will compare how well doctors, AI alone, and doctors using AI together can spot abnormalities, urgent findings, and classify diseases. The goal is to red…
Sponsor: Yaou Liu • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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Can a simple leg machine help stiff muscles and walking? new study aims to find out.
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether using a passive kinesiotherapy device on the legs for 30 minutes can immediately reduce muscle stiffness (spasticity) and improve walking in people with conditions like cerebral palsy, stroke-related weakness, or spinal cord issues. About 80 participan…
Phase: NA • Sponsor: Fernanda Trubian • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Spinal stimulation plus drug may restore arm function in paralysis
Symptom relief OngoingThis early study tests whether combining a spinal cord stimulator with the drug buspirone can improve arm and hand movement in people with cervical spinal cord injury. Twelve participants will receive both the device and the drug, and their motor function will be formally assesse…
Phase: PHASE1, PHASE2 • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC