Pyloric stenosis
MONDO:0001561Narrowing of the pyloric lumen caused either by hypertrophy of the surrounding muscles or tissue scarring due to a chronic peptic ulcer.
Also known as: GOO, gastric outlet obstruction, pyloric stenosis, pyloric stenosis (disease)
33 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Can a Macrophage-Targeting drug supercharge CAR-T therapy?
Disease control Not yet recruitingThis trial tests whether adding a drug called axatilimab to standard CAR-T cell therapy can improve outcomes for people with high-risk large B-cell lymphomas. Axatilimab works by conditioning macrophages, a type of immune cell, to potentially help the CAR-T cells fight cancer mor…
Phase: PHASE1 • Sponsor: Northside Hospital, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New hope for rare lymphoma: drug combo targets tough cancer
Disease control Not yet recruitingThis study tests whether adding brentuximab vedotin to standard chemotherapy (R-CHP) works better for people newly diagnosed with a rare, aggressive lymphoma linked to the Epstein-Barr virus. About 25 adults will receive the combination and be followed for 2 years to see if the c…
Phase: PHASE2 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New imaging agent aims to light up hidden tumors
Diagnosis Not yet recruitingThis early-stage study will test a new radioactive tracer called [89Zr]DFO-YS5 in 40 people with nerve sheath tumors, bladder cancer, or other advanced solid tumors. The tracer is designed to bind to cancer cells and show up on PET scans, potentially making tumors easier to see. …
Phase: PHASE1 • Sponsor: Robert Flavell, MD, PhD • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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Magnets replace knives: new procedure eases stomach blockages
Symptom relief Not yet recruitingThis study tests a special magnet system to create a new passage between the stomach and small intestine in people with gastric outlet obstruction (a blockage that prevents food from leaving the stomach). The goal is to relieve symptoms without traditional surgery. Ten adults who…
Phase: NA • Sponsor: GT Metabolic Solutions, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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New balloon device aims to ease stomach blockages without surgery
Symptom relief Not yet recruitingThis study compares a new balloon-assisted technique to the standard water-injection method for creating a stomach-to-intestine bypass in people with gastric outlet obstruction. The blockage, often caused by advanced cancer, leads to nausea, vomiting, and malnutrition. The new ap…
Phase: NA • Sponsor: Changhai Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 15:04 UTC
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One-Click autofocus could speed up stomach scopes
Knowledge-focused Not yet recruitingThis study tests a new one-click autofocus system for magnifying endoscopy, which uses computer vision to automatically focus the camera during stomach exams. Researchers will compare it to the standard manual focus method in 93 patients with stomach diseases. The goal is to see …
Phase: NA • Sponsor: Shandong University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New study to track hidden salt and mineral imbalances in sick kids
Knowledge-focused Not yet recruitingThis study will look at 150 infants and children aged 1 month to 4 years who are admitted to a hospital gastroenterology unit with a gastrointestinal disease. The goal is to find out how common electrolyte disturbances (like low sodium or potassium) are in these children. By meas…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:41 UTC