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Pyloric stenosis
MONDO:0001561Narrowing of the pyloric lumen caused either by hypertrophy of the surrounding muscles or tissue scarring due to a chronic peptic ulcer.
Also known as: GOO, gastric outlet obstruction, pyloric stenosis, pyloric stenosis (disease)
33 clinical trials for this condition and its sub-types.
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Broader categories
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New drug shows promise in early trial for kids with deadly brain cancer
Disease control CompletedThis early-phase study tested an experimental drug called INCB7839 in 13 children whose high-grade gliomas (aggressive brain tumors) had come back or worsened after standard treatment. The main goals were to find a safe dose and check for side effects. The drug works by blocking …
Phase: PHASE1 • Sponsor: Pediatric Brain Tumor Consortium • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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New study pits two endoscopic techniques against each other for stomach blockage relief
Symptom relief CompletedThis study looked at 112 adults with stomach blockage caused by advanced cancer. It compared two less invasive procedures: one using an ultrasound-guided bypass and the other using a stent to open the blockage. The goal was to see which method better prevents the blockage from co…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Bypass without surgery: new scope procedure helps cancer patients eat again
Symptom relief CompletedThis study tested a new procedure that uses an endoscope to create a bypass around a stomach blockage caused by advanced cancer. The goal was to help people eat and drink without major surgery. Fifty-one participants with inoperable cancer and severe blockage were enrolled. The p…
Phase: NA • Sponsor: Boston Scientific Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Does a stomach tube prevent breathing problems in babies with pyloric stenosis?
Knowledge-focused CompletedThis study looks at whether placing a tube through the nose into the stomach (nasogastric tube) before surgery helps prevent breathing complications in infants with hypertrophic pyloric stenosis. The condition causes a blockage in the stomach outlet, leading to forceful vomiting.…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC