Pulmonary hypertension, primary, 4
MONDO:0014136Any primary pulmonary hypertension in which the cause of the disease is a mutation in the KCNK3 gene.
Also known as: KCNK3 primary pulmonary hypertension, primary pulmonary hypertension caused by mutation in KCNK3, pulmonary hypertension, primary, 4, pulmonary hypertension, primary, type 4, PPH4
22 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Could vinegar and fasting fix prediabetes cholesterol?
Disease control CompletedThis study tests whether taking date cider vinegar daily, alone or combined with 5:2 intermittent fasting, can improve cholesterol and other metabolic measures in adults with prediabetes and mild to moderate high cholesterol or blood pressure. Participants are randomly assigned t…
Phase: NA • Sponsor: University of Lahore • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Old drug, new hope for right heart failure?
Disease control CompletedThis study tested the drug spironolactone in 15 adults with chronic right-sided heart failure. The goal was to see if it is safe and can improve heart function and reduce stress on the heart. Participants took either the drug or a placebo to compare effects.
Phase: PHASE4 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Can breathing training help people with lung blood pressure?
Symptom relief CompletedThis study tested whether 8 weeks of inspiratory muscle training (breathing exercises using a device) could improve exercise capacity in 32 people with pulmonary hypertension. Participants were randomly assigned to either active training or a placebo version. The goal was to see …
Phase: NA • Sponsor: Federal University of São Paulo • Aim: Symptom relief
Last updated Jun 26, 2026 17:58 UTC
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Small study aims to unlock secrets of rare lung disease
Knowledge-focused CompletedThis completed Phase 1 study looked at 27 people with and without pulmonary hypertension to learn more about how blood vessel problems contribute to the disease. Researchers used heart catheterization, imaging, and blood tests to find biomarkers and understand disease mechanisms.…
Phase: PHASE1 • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC