Pulmonary edema
MONDO:0006932Accumulation of fluid in the lung tissues causing disturbance of the gas exchange that may lead to respiratory failure. It is caused by direct injury to the lung parenchyma or congestive heart failure. The symptoms may appear suddenly or gradually. Suddenly appearing symptoms include difficulty breathing, feeling of suffocation, and coughing associated with frothy sputum. Gradually appearing symptoms include difficulty breathing while lying in bed, shortness of breath during activity, and weight gain (in patients with congestive heart failure).
Also known as: edema, pulmonary
65 clinical trials for this condition and its sub-types, 27 tagged with Pulmonary edema itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pulmonary edema
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High altitude pulmonary edema 5 trials
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Oxygen showdown: tight vs. liberal targets in heart failure
Disease control CompletedThis study tested whether giving heart failure patients with fluid in their lungs a lower oxygen target (90% oxygen saturation) or a higher one (96%) leads to better outcomes. 122 patients were randomly assigned to one of the two groups in the emergency department. The goal was t…
Phase 2/3 • Sponsor: Copenhagen University Hospital, Hvidovre • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New pill timing may help heart failure patients flush salt after meals
Disease control CompletedThis study tested whether an extended-release version of the diuretic torsemide helps heart failure patients get rid of more salt after lunch compared to the standard immediate-release version. Twenty adults with stable heart failure took both forms in a random order, and researc…
Phase 4 • Sponsor: Sarfez Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Blood protein may help doctors spot cause of lung fluid
Diagnosis CompletedThis study tested whether measuring a protein called Clara cell protein 16 (CC16) in the blood can help doctors tell the difference between two types of lung fluid buildup: one caused by heart problems and another caused by lung injury. Researchers measured CC16 levels in 100 ICU…
Sponsor: Beni-Suef University • Aim: Diagnosis
Last updated Jun 27, 2026 08:10 UTC
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Which breathing machine works best for lung fluid emergencies?
Symptom relief CompletedThis study compared two breathing devices—CPAP and bilevel ventilation—in people with severe fluid buildup in the lungs (pulmonary edema). The goal was to see which device improves breathing faster. Participants were adults in respiratory distress. The results could help doctors …
Phase 3 • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Silent swimmers' lungs may hold water after races
Knowledge-focused CompletedThis study looked at 609 adults who completed an open-water swimming race and had no breathing problems. Researchers used lung ultrasound to check for extra fluid in the lungs. The goal was to find out how common hidden lung water is in swimmers who feel fine.
Sponsor: Dalarna County Council, Sweden • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC