Progressive familial heart block, type 1A
MONDO:0007240An autosomal dominant inherited cardiac bundle branch disorder which can progress to complete heart block.
Also known as: Lenegre's disease, PFHB1A, SCN5A progressive familial heart block, heart block, progressive, type IA, progressive familial heart block caused by mutation in SCN5A, progressive familial heart block, type IA, Cardiac conduction defect, nonprogressive, Cardiac conduction defect, progressive
50 clinical trials for this condition and its sub-types.
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Smarter heart pacing could cut hospital stays for heart failure patients
Disease control Not yet recruitingThis study tests a newer, more natural pacing method for people with heart failure and electrical problems in the heart. The approach uses the heart's own conduction system to improve coordination between chambers. Researchers will track patients for two years to see if this meth…
Sponsor: University of Pecs • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Pacemaker signals may unmask a rare heart condition
Diagnosis Not yet recruitingThis study explores whether the electrical signal measured by a pacemaker or defibrillator during implantation can help identify cardiac amyloidosis — a condition where abnormal proteins build up in the heart. Researchers will enroll 242 adults aged 65 and older who already need …
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jul 31, 2026 00:00 UTC
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Massive heart study aims to sharpen diagnosis and cut needless hospital stays
Knowledge-focused Not yet recruitingThis study follows 25,000 people referred to a specialized heart clinic with symptoms like chest pain or shortness of breath. Researchers will track which heart conditions are actually diagnosed and how patients are evaluated. The goal is to improve diagnostic accuracy and unders…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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New study aims to predict which heart patients will respond to therapy
Knowledge-focused Not yet recruitingThis study will observe 253 adults with heart rhythm problems who are scheduled for procedures like pacemakers or ablation. Researchers will use advanced imaging and AI tools to understand why some patients respond well to treatment while others do not. The goal is to find better…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Could heart and muscle disorders share a genetic cause?
Knowledge-focused Not yet recruitingThis study looks at whether people with certain heart rhythm disorders also carry genetic variants linked to a rare muscle condition called non-dystrophic myotonia. Researchers will review medical records of 570 participants and invite some for a neurological exam and electromyog…
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC