Preterm premature rupture of the membranes
MONDO:0012511A female reproductive system disease characterized by rupture of chorioamniotic membranes before 37 weeks of gestation.
Also known as: PPROM, preterm premature rupture of the membranes, preterm premature rupture of the membranes, susceptibility to
34 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Could a second dose of steroids help premature babies breathe easier?
Disease control TerminatedThis study investigates whether giving a repeat course of betamethasone, a steroid, to pregnant women with preterm premature rupture of membranes (PPROM) can improve health outcomes for their premature babies. The main goal is to see if it shortens the baby's stay in the neonatal…
Phase: PHASE2, PHASE3 • Sponsor: The University of Texas Medical Branch, Galveston • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Antibiotics at home after early water break: study stopped early
Disease control TerminatedThis study looked at whether giving pregnant people oral antibiotics at home could delay delivery after their water broke very early (between 18 and 23 weeks). The goal was to see if more people would stay pregnant for at least 28 days after the water broke. The study was stopped…
Phase: PHASE4 • Sponsor: University Hospitals Cleveland Medical Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Newborn death prediction tool for early membrane rupture falls short
Knowledge-focused TerminatedThis study tried to create a score that doctors could use before birth to predict whether a newborn would die after the mother's water broke very early (between 22 and 28 weeks of pregnancy). The researchers looked back at medical records of 34 women to find factors that might pr…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC