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Premenopausal osteoporosis

MONDO:0700047

Osteoporosis occurring in premenopausal women with existing fragility fractures, diseases or treatments known to cause bone loss or fractures.

1 clinical trial for this condition and its sub-types.

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Broader categories

Disease (680) Osteoporosis (264) Musculoskeletal system disorder (207) Hereditary disease (176) Bone disorder (51) Osteogenesis imperfecta (34) Bone resorption disease (22) Human disease (14) Osteochondrodysplasia (12) Metabolic bone disorder (9)

Not yet finished but already full! 1

New drug combo aims to rebuild bone in young women with rare osteoporosis

Disease control Ongoing

This study tests whether a monthly injection of romosozumab for one year, followed by another drug (denosumab) for another year, can safely increase bone density in 30 premenopausal women aged 18-48 who have osteoporosis without a known cause. The goal is to improve bone mass and…

Phase: PHASE2 • Sponsor: Columbia University • Aim: Disease control

Last updated Jun 27, 2026 09:09 UTC