New drug combo aims to rebuild bone in young women with rare osteoporosis
NCT ID NCT04800367
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a monthly injection of romosozumab for one year, followed by another drug (denosumab) for another year, can safely increase bone density in 30 premenopausal women aged 18-48 who have osteoporosis without a known cause. The goal is to improve bone mass and structure to reduce fracture risk. Participants will receive both medications in sequence and be monitored for bone changes.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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Columbia University Irving Medical Center
New York, New York, 10032, United States