New drug combo aims to rebuild bone in young women with rare osteoporosis

This study tests whether a monthly injection of romosozumab for one year, followed by another drug (denosumab) for another year, can safely increase bone density in 30 premenopausal women aged 18-48 who have osteoporosis without a known cause. The goal is to improve bone mass and structure to reduce fracture risk. Participants will receive both medications in sequence and be monitored for bone changes.