Postlingual non-syndromic genetic hearing loss
MONDO:0016298Postlingual non-syndromic genetic deafness is a rare, genetically highly heterogeneous otorhinolaryngologic disease, resulting from inner and/or middle ear or hearing nerve anomalies, typically characterized by progressive, bilateral, moderate to profound hearing loss (mean sensorineural hearing impairment equal to 40 dB or more for 500-, 1,000-, and 2,000-Hz frequency tones in the better ear) which occurs after the onset of speech development and is not associated with visible external ear abnormalities or any other medical problems. Language development is not initially significantly delayed.
Also known as: isolated postlingual genetic deafness, postlingual non-syndromic genetic deafness
10 clinical trials for this condition and its sub-types.
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Broader categories
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New algorithm fine-tunes cochlear implants to boost hearing in noisy places
Symptom relief CompletedThis study looked at whether a computer algorithm could improve how a cochlear implant is set for people who have one implant and a hearing aid in the other ear. Nine adults with severe hearing loss took part. The goal was to see if the new settings helped them hear better in qui…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Can virtual reality train cochlear implant users to hear where sounds are?
Symptom relief CompletedThis study tested a new virtual reality rehab program for adults with two cochlear implants who struggle to locate where sounds come from. Twelve participants completed 8 sessions over a month, using head movements and joystick feedback to practice sound localization. The goal wa…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated Jun 26, 2026 14:15 UTC