Post-COVID-19 disorder

This study will test hyperbaric oxygen therapy (HBOT) — breathing pure oxygen in a pressurized chamber — for over 30 conditions, including long COVID, Crohn's disease, frostbite, and multiple sclerosis. Researchers will track 100 patients to see if HBOT improves their quality of …

This trial tests whether inebilizumab, an antibody that wipes out certain immune cells called B cells, can improve physical function in adults with ME/CFS that started after an infection. Participants receive three infusions over six months, and the study measures changes in mobi…

This study tests whether two FDA-approved drugs, maraviroc and atorvastatin, can help people with Long COVID. 252 adults aged 18-65 with persistent symptoms will take either the drug combination or a placebo for 16 weeks. The main goal is to see if it reduces fatigue and improves…

This study investigates whether taking taurine—a natural amino acid found in the body and sold as a supplement—can help adolescents aged 10 to 17 who have Long COVID. Researchers will measure taurine levels in the blood and track changes in symptoms like fatigue, brain fog, and m…

This study tests whether a gentle, non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can improve quality of life, reduce fatigue, and clear brain fog in people with long COVID. Twenty adults with persistent fatigue or cognitive problem…

This study tests whether a low dose of aripiprazole, a drug used for psychiatric conditions, can reduce fatigue and improve thinking in adults with Long COVID or other post-infection syndromes. About 138 participants will receive either the drug or a placebo for 8 weeks, then swi…

This trial compares two approaches for managing long COVID fatigue: the Lightning Process, a mind-body program that teaches ways to change thought patterns and body responses, versus activity pacing, which helps balance rest and daily tasks. One hundred adults aged 18 to 65 with …

This study tests whether a natural supplement (made from orange, grapefruit, olive leaf, and other plant extracts) combined with a personalized exercise program can help people with long COVID. The trial will include 40 adults who still have symptoms like inflammation and fatigue…

This study tests whether a whole-body electrostimulation suit can reduce fatigue and improve physical function in people with Long COVID. 30 adults with persistent symptoms will be randomly assigned to receive either active stimulation or a placebo version during 12 weekly sessio…

This phase 3 trial tests whether a single infusion of human umbilical cord blood, called REGENECYTE, can reduce fatigue in people with Long COVID. Sixty adults with post-COVID condition will receive either the cord blood or a placebo (salt water) and be monitored for changes in f…

This study uses a special PET scan to look for signs of inflammation in the brains of people with Post-COVID syndrome. Researchers want to learn more about why some people have long-lasting symptoms after a COVID-19 infection. Ten Mayo Clinic patients who had COVID-19 and are exp…