Pneumococcal meningitis
MONDO:0006913An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with otitis media; mastoiditis; sinusitis; respiratory tract infections; sickle cell disease (anemia, sickle cell); skull fractures; and other disorders. Clinical manifestations include fever; headache; neck stiffness; and somnolence followed by seizures; focal neurologic deficits (notably deafness); and coma. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)
Also known as: Streptococcus pneumoniae caused infectious meningitis, Streptococcus pneumoniae infectious meningitis
11 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New vaccine aims to shield older adults from pneumonia
⭐️ VACCINE ⭐️ CompletedThis study tested a new vaccine called Pn-MAPS30plus to see if it is safe and helps the body fight pneumonia-causing bacteria. It involved 127 healthy adults aged 50 to 64. The vaccine is designed to protect against more types of the bacteria than current vaccines.
Phase: PHASE1 • Sponsor: GlaxoSmithKline • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 13:02 UTC
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New vaccine aims to shield High-Risk adults from pneumococcal disease
⭐️ VACCINE ⭐️ CompletedThis completed Phase 3 study tested a new vaccine called V116 in 518 adults aged 18 to 64 who are at increased risk for pneumococcal disease due to conditions like diabetes or chronic lung disease. The vaccine targets 21 strains of the bacteria that cause pneumonia and other infe…
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 09:09 UTC
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New vaccine shows promise in protecting older adults from pneumococcal disease
Prevention CompletedThis study tested a new vaccine called V116 in adults aged 50 and older to see if it is safe and works better than the current vaccine (PPSV23) at preventing pneumococcal disease, which can cause pneumonia and other serious infections. About 1,500 healthy adults received either V…
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Prevention
Last updated Jun 27, 2026 09:09 UTC
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MRI contrast dye may skew brain scans, study finds
Knowledge-focused CompletedThis study looked at how gadolinium, a dye used in MRI scans, changes the QSM signal in the brain's white matter. 73 patients with inflammatory central nervous system conditions had MRI scans before and after receiving gadolinium. The goal was to measure any differences in the si…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC