Pityriasis rubra pilaris
MONDO:0100017A group of skin conditions that cause constant inflammation and scaling of the skin. People with PRP have reddish, scaly patches that may occur everywhere on the body, or only on certain areas. Some people with PRP also develop thickened skin on the underside of the hands and feet (palmoplantar keratoderma), various nail abnormalities, and/or thinning of the hair. There are several types of PRP classified by age when symptoms begin, body areas involved, and whether other conditions are present. This condition occurs in adults (adult onset PRP) as well as children (juvenile onset PRP).
11 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Can a blood clot or platelet fibrin help save a tooth that failed root canal?
Disease control Not yet recruitingThis trial tests whether different scaffolds—a blood clot or various platelet-rich fibrin preparations—can improve healing in teeth that need a second root canal treatment. Sixty participants will receive one of four scaffolds during the procedure and be followed for a year. The …
Sponsor: Kırıkkale University • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Could stem cells from shoulder tissue boost rotator cuff healing?
Disease control Not yet recruitingThis study looks at whether adding stem cells from the shoulder bursa and platelet-rich plasma (PRP) to standard rotator cuff repair helps the tendon heal better. About 200 adults with full-thickness supraspinatus tears will be followed for a year. Researchers will compare those …
Phase: NA • Sponsor: National and Kapodistrian University of Athens • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New hope for rare skin disease: bimzelx trial launches
Disease control Not yet recruitingThis study tests whether the drug Bimzelx (bimekizumab) can improve skin symptoms in adults with pityriasis rubra pilaris, a rare condition causing red, scaly patches. Researchers will enroll 12 participants and measure how many achieve at least 75% improvement in skin severity a…
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC