Pityriasis rubra pilaris
MONDO:0100017A group of skin conditions that cause constant inflammation and scaling of the skin. People with PRP have reddish, scaly patches that may occur everywhere on the body, or only on certain areas. Some people with PRP also develop thickened skin on the underside of the hands and feet (palmoplantar keratoderma), various nail abnormalities, and/or thinning of the hair. There are several types of PRP classified by age when symptoms begin, body areas involved, and whether other conditions are present. This condition occurs in adults (adult onset PRP) as well as children (juvenile onset PRP).
17 clinical trials for this condition and its sub-types.
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Broader categories
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Promising drug shows hope for rare skin condition
Disease control CompletedThis study tested a drug called deucravacitinib in 7 adults with pityriasis rubra pilaris, a rare skin disease that causes red, scaly patches. The goal was to see if the drug safely improves skin symptoms and itching over 24 weeks. Researchers also looked for unique markers in th…
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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PRP injection shows promise for shoulder tendon healing
Disease control CompletedThis study tested whether platelet-rich plasma (PRP) can improve tendon healing in people with a torn rotator cuff. Forty adults having arthroscopic repair surgery were split into two groups: one received PRP during surgery, the other did not. Researchers compared tendon tissue s…
Phase: PHASE1 • Sponsor: Aristotle University Of Thessaloniki • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Platelet-Rich plasma may beat steroids for shoulder arthritis pain
Symptom relief CompletedThis study tested whether a shot of platelet-rich plasma (PRP) from a person's own blood works better than a common steroid shot for shoulder arthritis pain. Fifty adults with mild to moderate shoulder osteoarthritis received either a PRP or steroid injection. Researchers measure…
Phase: PHASE3 • Sponsor: Walter Reed National Military Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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AI could cut skin specialist wait times, study hints
Knowledge-focused CompletedThis study tested an artificial intelligence algorithm designed to help primary care doctors decide whether a patient with a skin condition really needs to see a dermatologist. Researchers enrolled 200 adults with skin problems and had their doctors take photos of the affected ar…
Sponsor: AI Labs Group S.L • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC