Pelvic organ prolapse
MONDO:0000082Abnormal descent of a pelvic organ resulting in the protrusion of the organ beyond its normal anatomical confines. Symptoms often include vaginal discomfort, dyspareunia; urinary stress incontinence; and fecal incontinence.
105 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Robot vs. vaginal surgery for prolapse: which is better? trial stopped early.
Disease control TerminatedThis study compared two surgical repairs for pelvic organ prolapse (when organs like the bladder or uterus drop into the vagina). One method uses a robot to place mesh inside the abdomen; the other uses stitches through the vagina to tighten natural ligaments. The trial enrolled …
Phase: NA • Sponsor: Loma Linda University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Pelvic prolapse surgery showdown: which method causes less leakage?
Disease control TerminatedThis study compared two surgical procedures for treating pelvic organ prolapse in women aged 50-80. One method uses a vaginal approach (sacrospinofixation) and the other uses keyhole surgery through the abdomen (laparoscopic promontofixation). The goal was to see which causes les…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Tiny trial on preventive bladder sling halted early — no clear answers
Prevention TerminatedThis study looked at women with pelvic organ prolapse who also had hidden (occult) stress urinary incontinence — leakage that doesn't show up on standard tests. The goal was to see if placing a TOT sling during prolapse surgery could prevent incontinence from appearing later. The…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated Jun 28, 2026 00:00 UTC
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Mesh study follows patients for years after prolapse surgery
Knowledge-focused TerminatedThis study followed 39 women who had surgery for pelvic organ prolapse using Restorelle mesh. The goal was to track safety and how well the mesh worked over 5 to 8 years after surgery. No new treatment was given—just routine check-ups to see if any further surgery was needed.
Sponsor: Coloplast A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New imaging method aims to personalize pelvic floor disorder treatments
Knowledge-focused TerminatedThis study tested a new way to map the pelvic cavity in women using MRI and a special vaginal pressure probe. The goal was to better understand each woman's pelvic tissue characteristics so treatments like surgery or rehabilitation could be personalized. Only one participant was …
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Hormone cream study aims to unlock pelvic floor secrets
Knowledge-focused TerminatedThis study looked at how hormones influence vaginal tissue in women with pelvic organ prolapse (POP), a condition where pelvic organs slip out of place. Researchers compared postmenopausal women using estrogen cream or placebo to reproductive-age women, examining tissue samples f…
Phase: PHASE4 • Sponsor: The University of Texas Medical Branch, Galveston • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC